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ccnh.L cyclin H L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 394356, updated on 4-Nov-2024

Summary

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Official Symbol
ccnh.L
Official Full Name
cyclin H L homeolog
Primary source
Xenbase:XB-GENE-922574
Locus tag
XELAEV_18008092mg
See related
EnsemblRapid:ENSXLAG00005005932 AllianceGenome:Xenbase:XB-GENE-922574
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
ccnh; ccnh-A
Summary
Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to act upstream of or within DNA-templated transcription; regulation of cyclin-dependent protein serine/threonine kinase activity; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIK complex. Orthologous to human CCNH (cyclin H). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ccnh.L in Genome Data Viewer
Location:
chromosome: 1L
Exon count:
9
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1L NC_054371.1 (195575939..195584963)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1L NC_030724.1 (182435104..182444197)

Chromosome 1L - NC_054371.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121395339 Neighboring gene transmembrane protein 161B Neighboring gene RAS p21 protein activator (GTPase activating protein) 1 L homeolog Neighboring gene small nucleolar RNA Z39 Neighboring gene cytochrome c oxidase subunit VIIc L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. p40MO15 associates with a p36 subunit and requires both nuclear translocation and Thr176 phosphorylation to generate cdk-activating kinase activity in Xenopus oocytes. Labbé JC, et al. EMBO J, 1994 Nov 1. PMID 7957080, Free PMC Article
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC130881

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase regulator activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of cyclin-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of transcription factor TFIIK complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cyclin-H
Names
MO15-associated protein
p36

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001087583.1 → NP_001081052.1  cyclin-H

    See identical proteins and their annotated locations for NP_001081052.1

    Status: PROVISIONAL

    Source sequence(s)
    U20505
    UniProtKB/Swiss-Prot
    P51947
    UniProtKB/TrEMBL
    A0A974E2E6, Q3KQ83
    Related
    ENSXLAP00005017698.1, ENSXLAT00005017994.1
    Conserved Domains (3) summary
    TIGR00569
    Location:2 → 308
    ccl1; cyclin ccl1
    smart00385
    Location:62 → 152
    CYCLIN; domain present in cyclins, TFIIB and Retinoblastoma
    pfam16899
    Location:162 → 262
    Cyclin_C_2; Cyclin C-terminal domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054371.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    195575939..195584963
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P51947.1 GenPept UniProtKB/Swiss-Prot:P51947

Gene LinkOut

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