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otx1.L orthodenticle homeobox 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 394326, updated on 18-Sep-2024

Summary

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Official Symbol
otx1.L
Official Full Name
orthodenticle homeobox 1 L homeolog
Primary source
Xenbase:XB-GENE-939807
Locus tag
XELAEV_18026512mg
See related
EnsemblRapid:ENSXLAG00005013702
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
otx1; xotx1; otx1-A
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Genomic context

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See otx1.L in Genome Data Viewer
Location:
chromosome: 5L
Exon count:
7
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5L NC_054379.1 (31685746..31693533, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5L NC_030732.1 (30924684..30932478, complement)

Chromosome 5L - NC_054379.1Genomic Context describing neighboring genes Neighboring gene malate dehydrogenase 1 L homeolog Neighboring gene WD repeat containing planar cell polarity effector L homeolog Neighboring gene EH domain binding protein 1 L homeolog Neighboring gene uncharacterized LOC108716591

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification and evolution of molecular domains involved in differentiating the cement gland-promoting activity of Otx proteins in Xenopus laevis. Mancini P, et al. Mech Dev, 2013 Nov-Dec. PMID 24056062
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A histidine stretch disrupts continuity in Otx1 determining its loss of cement gland-promoting activity.
    Title: Identification and evolution of molecular domains involved in differentiating the cement gland-promoting activity of Otx proteins in Xenopus laevis.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
orthodenticle homeobox 1 L homeolog
Names
transcription factor Otx1, orthodenticle homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001087540.1 → NP_001081009.1  orthodenticle homeobox 1 L homeolog

    See identical proteins and their annotated locations for NP_001081009.1

    Status: PROVISIONAL

    Source sequence(s)
    AY029294
    UniProtKB/TrEMBL
    Q98SI7
    Related
    ENSXLAP00005040465.1, ENSXLAT00005041388.1
    Conserved Domains (2) summary
    pfam00046
    Location:42 → 94
    Homeobox; Homeobox domain
    pfam03529
    Location:180 → 263
    TF_Otx; Otx1 transcription factor

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054379.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    31685746..31693533 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018261692.2 → XP_018117181.1  orthodenticle homeobox 1 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974CTX2, Q0IH93

  2. XM_018261691.2 → XP_018117180.1  orthodenticle homeobox 1 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974CTX2, Q0IH93

  3. XM_018261693.2 → XP_018117182.1  orthodenticle homeobox 1 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974CTX2, Q0IH93
Nucleotide Protein Strain
Heading Accession and Version

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