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sfrp1.L secreted frizzled-related protein 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 394302, updated on 17-Aug-2024

Summary

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Official Symbol
sfrp1.L
Official Full Name
secreted frizzled-related protein 1 L homeolog
Primary source
Xenbase:XB-GENE-865777
Locus tag
XELAEV_18018658mg
See related
EnsemblRapid:ENSXLAG00005002840
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
frp; frp1; frzA; XfrzA; frp-1; sarp2; sfrp1; sfrp1-a
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Genomic context

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Location:
chromosome: 3L
Exon count:
3
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (135006737..135024378, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3L NC_030728.1 (119670142..119687809, complement)

Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene indoleamine 2,3-dioxygenase 1 L homeolog Neighboring gene transcriptional and immune response regulator L homeolog Neighboring gene golgin A7 L homeolog Neighboring gene R3H and coiled-coil domain-containing protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. sfrp1 promotes cardiomyocyte differentiation in Xenopus via negative-feedback regulation of Wnt signalling. Gibb N, et al. Development, 2013 Apr. PMID 23482489, Free PMC Article
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. sfrp1 promotes cardiomyocyte differentiation in Xenopus via negative-feedback regulation of Wnt signalling.
    Title: sfrp1 promotes cardiomyocyte differentiation in Xenopus via negative-feedback regulation of Wnt signalling.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
secreted frizzled-related protein 1 L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001087488.1 → NP_001080957.1  secreted frizzled-related protein 1 L homeolog precursor

    See identical proteins and their annotated locations for NP_001080957.1

    Status: PROVISIONAL

    Source sequence(s)
    AF049908
    UniProtKB/TrEMBL
    A0A974DE36, Q9YI24
    Related
    ENSXLAP00005008473.1, ENSXLAT00005008599.1
    Conserved Domains (2) summary
    cd03580
    Location:180 → 303
    NTR_Sfrp1_like; NTR domain, Secreted frizzled-related protein (Sfrp) 1-like subfamily; composed of proteins similar to human Sfrp1, Sfrp2 and Sfrp5. Sfrps are soluble proteins containing an NTR domain C-terminal to a cysteine-rich Frizzled domain. They show diverse ...
    cl02447
    Location:48 → 172
    CRD_FZ; CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    135006737..135024378 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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