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nme4 NME/NM23 nucleoside diphosphate kinase 4 [ Danio rerio (zebrafish) ]

Gene ID: 394170, updated on 10-Oct-2024

Summary

Official Symbol
nme4provided by ZNC
Official Full Name
NME/NM23 nucleoside diphosphate kinase 4provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1043
See related
Ensembl:ENSDARG00000088390 AllianceGenome:ZFIN:ZDB-GENE-040426-1043
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:56482
Summary
Predicted to enable nucleoside diphosphate kinase activity. Predicted to act upstream of or within nucleotide metabolic process. Is expressed in several structures, including axis; endoderm; gonad; pigment cell; and retina. Orthologous to human NME4 (NME/NM23 nucleoside diphosphate kinase 4). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See nme4 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (15042630..15081977, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (14892938..14932074, complement)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene growth arrest and DNA-damage-inducible, gamma interacting protein 1 Neighboring gene nuclear factor I/Xb Neighboring gene uncharacterized LOC110439336 Neighboring gene exportin 6 Neighboring gene adenine nucleotide translocase lysine methyltransferase

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC56482

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleoside diphosphate kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables nucleoside diphosphate kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within CTP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within GTP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within UTP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
nucleoside diphosphate kinase, mitochondrial
Names
NM23-Z4
non-metastatic cells 4, protein expressed in
NP_957489.2
XP_017209189.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201195.2NP_957489.2  nucleoside diphosphate kinase, mitochondrial

    Status: VALIDATED

    Source sequence(s)
    CT961050, CU464084
    Related
    ENSDARP00000151340.1, ENSDART00000192532.1

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    15042630..15081977 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017353700.3XP_017209189.1  nucleoside diphosphate kinase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8M1PE77, A0A8M6YXW7, Q7ZUI5

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394523.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    277..2086 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)