U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Est-P Esterase P [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39393, updated on 18-Sep-2024

Summary

Official Symbol
Est-Pprovided by FlyBase
Official Full Name
Esterase Pprovided by FlyBase
Primary source
FLYBASE:FBgn0000594
Locus tag
Dmel_CG17148
See related
AllianceGenome:FB:FBgn0000594
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG17148; Dmel\CG17148; Est-5; EST-5; Est-7; est-P; Est7; EST7; EstP; ESTP; psiEst-6; PsiEst-6; yEst-6; yEst6
Summary
Enables carboxylic ester hydrolase activity and serine hydrolase activity. Is expressed in organism. Orthologous to several human genes including CES1 (carboxylesterase 1); CES2 (carboxylesterase 2); and CES3 (carboxylesterase 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Est-P in Genome Data Viewer
Location:
69A1-69A1; 3-38 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (12190733..12192528)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (12183833..12185628)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Myo-inositol oxygenase Neighboring gene Esterase 6 Neighboring gene thoc6 Neighboring gene long non-coding RNA:CR45746 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

General protein information

Preferred Names
esterase P
Names
CG17148-PA
Est-P-PA
NP_788501.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    12190733..12192528
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_176323.2NP_788501.1  esterase P [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788501.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P18167, Q32KD6, Q9VTV0
    Related
    FBpp0075736
    Conserved Domains (2) summary
    COG0657
    Location:107240
    Aes; Acetyl esterase/lipase [Lipid transport and metabolism]
    cd00312
    Location:26537
    Esterase_lipase; Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These ...