cdc23 CDC23 (cell division cycle 23, yeast, homolog) [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cdc23provided by ZNC
Official Full Name: CDC23 (cell division cycle 23, yeast, homolog)provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-866
See related: Ensembl:ENSDARG00000044484 AllianceGenome:ZFIN:ZDB-GENE-040426-866
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:56013
Summary: Predicted to be involved in cell division; cellular protein metabolic process; and regulation of mitotic sister chromatid separation. Predicted to act upstream of or within regulation of mitotic metaphase/anaphase transition. Predicted to be part of anaphase-promoting complex. Predicted to be active in cytoplasm. Orthologous to human CDC23 (cell division cycle 23). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 21

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	21	NC_007132.7 (34849423..34879272)
105	previous assembly	GRCz10 (GCF_000002035.5)	21	NC_007132.6 (34814933..34844782)

Chromosome 21 - NC_007132.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in anaphase-promoting complex-dependent catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in cell division	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within cell division	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of mitotic metaphase/anaphase transition	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein ubiquitination	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of anaphase-promoting complex	IBA Inferred from Biological aspect of Ancestor more info
part_of anaphase-promoting complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cell division cycle protein 23 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200933.1 → NP_957227.1 cell division cycle protein 23 homolog

See identical proteins and their annotated locations for NP_957227.1

Status: PROVISIONAL

Source sequence(s)

BC045861

UniProtKB/TrEMBL

A9JTC3, F6P0T3, Q7ZVH3

Related

ENSDARP00000065324.4, ENSDART00000065325.5

Conserved Domains (4) summary

sd00006
Location:314 → 342

TPR; TPR repeat [structural motif]

pfam00515
Location:350 → 381

TPR_1; Tetratricopeptide repeat

pfam04049
Location:11 → 137

ANAPC8; Anaphase promoting complex subunit 8 / Cdc23

pfam13414
Location:350 → 413

TPR_11; TPR repeat