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bcas3 BCAS3 microtubule associated cell migration factor [ Danio rerio (zebrafish) ]

Gene ID: 393594, updated on 12-Sep-2024

Summary

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Official Symbol
bcas3provided by ZNC
Official Full Name
BCAS3 microtubule associated cell migration factorprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1257
See related
Ensembl:ENSDARG00000090764 AllianceGenome:ZFIN:ZDB-GENE-040426-1257
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:63764
Summary
Predicted to be involved in response to starvation. Predicted to be active in cytoplasm. Orthologous to human BCAS3 (BCAS3 microtubule associated cell migration factor). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See bcas3 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (26941075..27354759)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (27008147..27421883)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 9 Neighboring gene protein phosphatase, Mg2+/Mn2+ dependent, 1Da Neighboring gene uncharacterized LOC110437907 Neighboring gene uncharacterized LOC137487757 Neighboring gene si:ch211-229g11.5 Neighboring gene uncharacterized LOC137487756 Neighboring gene si:ch211-229g11.6 Neighboring gene T-box transcription factor 2b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. A conserved role for the ALS-linked splicing factor SFPQ in repression of pathogenic cryptic last exons. Gordon PM, et al. Nat Commun, 2021 Mar 26. PMID 33771997, Free PMC Article
  2. Genome Sequencing of the Japanese Eel (Anguilla japonica) for Comparative Genomic Studies on tbx4 and a tbx4 Gene Cluster in Teleost Fishes. Chen W, et al. Mar Drugs, 2019 Jul 20. PMID 31330852, Free PMC Article
  3. Evolutionary context can clarify gene names: Teleosts as a case study. Gasanov EV, et al. Bioessays, 2021 Jun. PMID 33829511
  4. The first characterization of multidrug and toxin extrusion (MATE/SLC47) proteins in zebrafish (Danio rerio). Lončar J, et al. Sci Rep, 2016 Jun 30. PMID 27357367, Free PMC Article
  5. Non-nuclear Pool of Splicing Factor SFPQ Regulates Axonal Transcripts Required for Normal Motor Development. Thomas-Jinu S, et al. Neuron, 2017 Apr 19. PMID 28392072, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC63764

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within autophagy IEA
Inferred from Electronic Annotation
more info
  
involved_in response to starvation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
BCAS3 microtubule associated cell migration factor
Names
breast carcinoma amplified sequence 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200622.1 → NP_956916.1  BCAS3 microtubule associated cell migration factor

    See identical proteins and their annotated locations for NP_956916.1

    Status: PROVISIONAL

    Source sequence(s)
    BC056819
    UniProtKB/TrEMBL
    Q6PGV4
    Related
    ENSDARP00000123733.1, ENSDART00000149957.3
    Conserved Domains (3) summary
    COG2319
    Location:297 → 419
    WD40; WD40 repeat [General function prediction only]
    pfam12490
    Location:517 → 734
    BCAS3; Breast carcinoma amplified sequence 3
    cl02567
    Location:339 → 445
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    26941075..27354759
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021481360.2 → XP_021337035.1  BCAS3 microtubule associated cell migration factor isoform X1

    UniProtKB/TrEMBL
    A0A8M9QPS4
    Conserved Domains (2) summary
    smart00320
    Location:339 → 374
    WD40; WD40 repeats
    pfam12490
    Location:517 → 749
    BCAS3; Breast carcinoma amplified sequence 3

  2. XM_005157643.5 → XP_005157700.1  BCAS3 microtubule associated cell migration factor isoform X2

    UniProtKB/TrEMBL
    A0A8M2B3U5
    Conserved Domains (3) summary
    COG2319
    Location:297 → 419
    WD40; WD40 repeat [General function prediction only]
    pfam12490
    Location:517 → 749
    BCAS3; Breast carcinoma amplified sequence 3
    cl02567
    Location:339 → 445
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. XM_005157644.5 → XP_005157701.1  BCAS3 microtubule associated cell migration factor isoform X3

    UniProtKB/TrEMBL
    A0A8M2B3Z7
    Conserved Domains (3) summary
    COG2319
    Location:297 → 419
    WD40; WD40 repeat [General function prediction only]
    pfam12490
    Location:517 → 734
    BCAS3; Breast carcinoma amplified sequence 3
    cl02567
    Location:339 → 445
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  4. XM_068213492.1 → XP_068069593.1  BCAS3 microtubule associated cell migration factor isoform X5

    Related
    ENSDARP00000148019.1, ENSDART00000189636.1

  5. XM_068213491.1 → XP_068069592.1  BCAS3 microtubule associated cell migration factor isoform X4

    Related
    ENSDARP00000071640.4, ENSDART00000077172.6

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394948.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    3556..22520
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394949.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    40001..66667
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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