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slc25a27 solute carrier family 25 member 27 [ Danio rerio (zebrafish) ]

Gene ID: 393312, updated on 17-Aug-2024

Summary

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Official Symbol
slc25a27provided by ZNC
Official Full Name
solute carrier family 25 member 27provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1290
See related
Ensembl:ENSDARG00000042873 AllianceGenome:ZFIN:ZDB-GENE-040426-1290
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:63899
Summary
Predicted to be involved in response to cold. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including Kupffer's vesicle; brain; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human SLC25A27 (solute carrier family 25 member 27). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 20
Exon count:
9
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (36801804..36808813, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (36898925..36905934, complement)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene nuclear receptor coactivator 1 Neighboring gene peptidyl-tRNA hydrolase domain containing 1 Neighboring gene ABRA C-terminal like Neighboring gene hdc homolog, cell cycle regulator

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. An engineering approach to extending lifespan in C. elegans. Sagi D, et al. PLoS Genet, 2012. PMID 22737090, Free PMC Article
  2. Exploring uncoupling proteins and antioxidant mechanisms under acute cold exposure in brains of fish. Tseng YC, et al. PLoS One, 2011 Mar 25. PMID 21464954, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Clone Names

  • MGC63899

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in response to cold IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mitochondrial uncoupling protein 4
Names
Ucp4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200341.1 → NP_956635.1  mitochondrial uncoupling protein 4

    See identical proteins and their annotated locations for NP_956635.1

    Status: PROVISIONAL

    Source sequence(s)
    BC053139
    UniProtKB/TrEMBL
    Q7T3F5
    Related
    ENSDARP00000062924.3, ENSDART00000062925.4
    Conserved Domains (2) summary
    PTZ00169
    Location:16 → 310
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    pfam00153
    Location:118 → 213
    Mito_carr; Mitochondrial carrier protein

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    36801804..36808813 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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