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rbm28 RNA binding motif protein 28 [ Danio rerio (zebrafish) ]

Gene ID: 393291, updated on 2-Nov-2024

Summary

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Official Symbol
rbm28provided by ZNC
Official Full Name
RNA binding motif protein 28provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-960
See related
Ensembl:ENSDARG00000025332 AllianceGenome:ZFIN:ZDB-GENE-040426-960
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:56258
Summary
Predicted to enable RNA binding activity. Predicted to be located in nucleus. Predicted to be active in nucleolus. Human ortholog(s) of this gene implicated in alopecia, neurologic defects, and endocrinopathy syndrome. Orthologous to human RBM28 (RNA binding motif protein 28). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See rbm28 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (10692945..10713414, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (10724227..10744696, complement)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene microRNA mir-129-3 Neighboring gene leptin a Neighboring gene microtubule associated monooxygenase, calponin and LIM domain containing 3a Neighboring gene tetratricopeptide repeat domain 38

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Loss of Function Mutations in NNT Are Associated With Left Ventricular Noncompaction. Bainbridge MN, et al. Circ Cardiovasc Genet, 2015 Aug. PMID 26025024, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC56258

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
RNA-binding protein 28

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200321.1 → NP_956615.1  RNA-binding protein 28

    See identical proteins and their annotated locations for NP_956615.1

    Status: PROVISIONAL

    Source sequence(s)
    BC051781
    UniProtKB/TrEMBL
    Q7ZTZ1
    Related
    ENSDARP00000034794.4, ENSDART00000034817.5
    Conserved Domains (5) summary
    cd12413
    Location:5 → 77
    RRM1_RBM28_like; RNA recognition motif 1 in RNA-binding protein 28 (RBM28) and similar proteins
    cd12414
    Location:237 → 312
    RRM2_RBM28_like; RNA recognition motif 2 in RNA-binding protein 28 (RBM28) and similar proteins
    cd12415
    Location:438 → 520
    RRM3_RBM28_like; RNA recognition motif 3 in RNA-binding protein 28 (RBM28) and similar proteins
    cd12416
    Location:590 → 683
    RRM4_RBM28_like; RNA recognition motif 4 in RNA-binding protein 28 (RBM28) and similar proteins
    TIGR01661
    Location:2 → 316
    ELAV_HUD_SF; ELAV/HuD family splicing factor

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    10692945..10713414 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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