U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

tuba8l4 tubulin, alpha 8 like 4 [ Danio rerio (zebrafish) ]

Gene ID: 393154, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
tuba8l4provided by ZNC
Official Full Name
tubulin, alpha 8 like 4provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-860
See related
Ensembl:ENSDARG00000006260 AllianceGenome:ZFIN:ZDB-GENE-040426-860
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fa93f03; zgc:55990; zgc:85669; wu:fa93f03
Summary
Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to act upstream of or within microtubule-based process. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm and microtubule. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See tuba8l4 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (6972958..6976107, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (6815789..6818938, complement)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene Rap guanine nucleotide exchange factor 4b Neighboring gene protein kinase Npk Neighboring gene si:ch211-114n24.6 Neighboring gene bridging integrator 1b

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Conservation of structure and function in vertebrate c-FLIP proteins despite rapid evolutionary change. Sakamaki K, et al. Biochem Biophys Rep, 2015 Sep. PMID 29124180, Free PMC Article
  2. Nonsense mutation in the WDR73 gene is associated with Galloway-Mowat syndrome. Ben-Omran T, et al. J Med Genet, 2015 Jun. PMID 25873735
  3. Reproductive toxicity of β-diketone antibiotic mixtures to zebrafish (Danio rerio). Wang X, et al. Ecotoxicol Environ Saf, 2017 Jul. PMID 28342328
  4. Proteomic analysis of zebrafish (Danio rerio) infected with infectious spleen and kidney necrosis virus. Xiong XP, et al. Dev Comp Immunol, 2011 Apr. PMID 21075138
  5. 4.1Ba is necessary for glutamatergic synapse formation in the sensorimotor circuit of developing zebrafish. Fierro J Jr, et al. PLoS One, 2018. PMID 30286167, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC55990

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within microtubule-based process IEA
Inferred from Electronic Annotation
more info
  
involved_in mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
is_active_in microtubule IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
tubulin, alpha 8 like 4

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200185.1 → NP_956479.1  tubulin, alpha 8 like 4

    See identical proteins and their annotated locations for NP_956479.1

    Status: PROVISIONAL

    Source sequence(s)
    BC045847
    UniProtKB/TrEMBL
    Q7ZVI6
    Related
    ENSDARP00000029933.7, ENSDART00000039443.9
    Conserved Domains (2) summary
    PTZ00335
    Location:1 → 440
    PTZ00335; tubulin alpha chain; Provisional
    cd02186
    Location:2 → 435
    alpha_tubulin; The alpha-tubulin family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    6972958..6976107 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools