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CG6418 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39218, updated on 2-Nov-2024

Summary

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Official Symbol
CG6418provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0036104
Locus tag
Dmel_CG6418
See related
AllianceGenome:FB:FBgn0036104
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
cg6418; Dmel\CG6418; DmRH27
Summary
Predicted to enable RNA binding activity and RNA helicase activity. Predicted to be involved in protein localization. Predicted to be active in nucleus. Is expressed in several structures, including ganglia; larval nervous system; pole plasm; and tracheal primordium. Orthologous to human DDX42 (DEAD-box helicase 42). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See CG6418 in Genome Data Viewer
Location:
67F1-67F1; 3-33 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (10876315..10879037, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (10869415..10872137, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45246 Neighboring gene tonalli Neighboring gene long non-coding RNA:CR45169 Neighboring gene Biogenesis of lysosome-related organelles complex 1, subunit 4 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Drosophila trithorax group gene tonalli (tna) interacts genetically with the Brahma remodeling complex and encodes an SP-RING finger protein. Gutiérrez L, et al. Development, 2003 Jan. PMID 12466201
  2. DDX56 Binds to Chikungunya Virus RNA To Control Infection. Taschuk F, et al. mBio, 2020 Oct 27. PMID 33109765, Free PMC Article
  3. Stem-loop recognition by DDX17 facilitates miRNA processing and antiviral defense. Moy RH, et al. Cell, 2014 Aug 14. PMID 25126784, Free PMC Article
  4. Evolution of intron/exon structure of DEAD helicase family genes in Arabidopsis, Caenorhabditis, and Drosophila. Boudet N, et al. Genome Res, 2001 Dec. PMID 11731501, Free PMC Article
  5. RNA silencing in the antiviral innate immune defence--role of DEAD-box RNA helicases. Ulvila J, et al. Scand J Immunol, 2010 Mar. PMID 20415780

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables RNA helicase activity IEA
Inferred from Electronic Annotation
more info
  
enables RNA helicase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein localization ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG6418-PB
NP_648413.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    10876315..10879037 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140156.3 → NP_648413.1  uncharacterized protein Dmel_CG6418 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648413.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VTC1
    Related
    FBpp0076003
    Conserved Domains (3) summary
    smart00487
    Location:284 → 489
    DEXDc; DEAD-like helicases superfamily
    cd00268
    Location:271 → 475
    DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
    pfam00271
    Location:504 → 609
    Helicase_C; Helicase conserved C-terminal domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VTC1 Q9VTC1

Gene LinkOut

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