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CG3434 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39098, updated on 2-Nov-2024

Summary

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Official Symbol
CG3434provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0036000
Locus tag
Dmel_CG3434
See related
AllianceGenome:FB:FBgn0036000
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG3434
Summary
Predicted to enable pentosyltransferase activity. Predicted to be involved in tRNA-guanine transglycosylation. Predicted to be part of tRNA-guanine transglycosylase complex. Is expressed in several structures, including Malpighian tubule primordium; dorsal pharyngeal muscle cell; embryonic/larval midgut; embryonic/larval midgut primordium; and mesoderm. Orthologous to human QTRT2 (queuine tRNA-ribosyltransferase accessory subunit 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

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See CG3434 in Genome Data Viewer
Location:
67B8-67B8; 3-29 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (9459369..9460799, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (9452469..9453899, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene pleiohomeotic like Neighboring gene antisense RNA:CR45873 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Ubiquitin carboxy-terminal hydrolase L5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. H/ACA snRNP-dependent ribosome biogenesis regulates translation of polyglutamine proteins. Breznak SM, et al. Sci Adv, 2023 Jun 23. PMID 37343092, Free PMC Article
  2. Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network. Orian A, et al. Genes Dev, 2003 May 1. PMID 12695332, Free PMC Article
  3. Systematic screening of a Drosophila ORF library in vivo uncovers Wnt/Wg pathway components. Schertel C, et al. Dev Cell, 2013 Apr 29. PMID 23583758
  4. In vivo profiling of the Zucchini proximal proteome in the Drosophila ovary. Nguyen TTM, et al. Development, 2023 Feb 15. PMID 36762624
  5. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables pentosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in tRNA-guanine transglycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tRNA-guanine transglycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of tRNA-guanine transglycosylase complex ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG3434-PA
NP_648320.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    9459369..9460799 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140063.5 → NP_648320.1  uncharacterized protein Dmel_CG3434 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648320.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VSZ6
    Related
    FBpp0076201
    Conserved Domains (1) summary
    pfam01702
    Location:139 → 382
    TGT; Queuine tRNA-ribosyltransferase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VSZ6.1 Q9VSZ6

Gene LinkOut

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