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CG5021 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39025, updated on 2-Nov-2024

Summary

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Official Symbol
CG5021provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0035944
Locus tag
Dmel_CG5021
See related
AllianceGenome:FB:FBgn0035944
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG5021
Summary
Predicted to be involved in protein secretion and vesicle-mediated transport. Predicted to be located in membrane. Predicted to be active in Golgi membrane. Is expressed in several structures, including adult head; anterior endoderm; embryonic/larval midgut primordium; gland; and gut section. Orthologous to several human genes including TVP23A (trans-golgi network vesicle protein 23 homolog A) and TVP23B (trans-golgi network vesicle protein 23 homolog B). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

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See CG5021 in Genome Data Viewer
Location:
66E5-66E5; 3-27 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (8966829..8968171)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (8959929..8961271)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Valyl-tRNA synthetase, mitochondrial Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene pixie

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The CrebA/Creb3-like transcription factors are major and direct regulators of secretory capacity. Fox RM, et al. J Cell Biol, 2010 Nov 1. PMID 21041443, Free PMC Article
  2. Identification of Drosophila centromere associated proteins by quantitative affinity purification-mass spectrometry. Barth TK, et al. Data Brief, 2015 Sep. PMID 26306323, Free PMC Article
  3. Endogenously imprinted genes in Drosophila melanogaster. McEachern LA, et al. Mol Genet Genomics, 2014 Aug. PMID 24658702
  4. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article
  5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in protein secretion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG5021-PA
CG5021-PB
CG5021-PC
CG5021-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    8966829..8968171
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001169919.2 → NP_001163390.1  uncharacterized protein Dmel_CG5021, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163390.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8IQC1, Q8SYV2, Q9VSR9
    UniProtKB/TrEMBL
    E1JI84, E4NKP0
    Conserved Domains (1) summary
    pfam05832
    Location:37 → 177
    DUF846; Eukaryotic protein of unknown function (DUF846)

  2. NM_001169920.2 → NP_001163391.1  uncharacterized protein Dmel_CG5021, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163391.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JI85, E4NKP0
    Conserved Domains (1) summary
    pfam05832
    Location:34 → 174
    DUF846; Eukaryotic protein of unknown function (DUF846)

  3. NM_168304.2 → NP_729433.1  uncharacterized protein Dmel_CG5021, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_729433.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E4NKP0, H0RND2
    Related
    FBpp0076241
    Conserved Domains (1) summary
    pfam05832
    Location:34 → 169
    DUF846; Eukaryotic protein of unknown function (DUF846)

  4. NM_140013.3 → NP_648270.2  uncharacterized protein Dmel_CG5021, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648270.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    E4NKP0
    Related
    FBpp0076240
    Conserved Domains (1) summary
    pfam05832
    Location:37 → 172
    DUF846; Eukaryotic protein of unknown function (DUF846)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
E1JI84 E1JI84
E1JI85 E1JI85
Q8IQC1.2 Q8IQC1

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