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CCDC9B coiled-coil domain containing 9B [ Homo sapiens (human) ]

Gene ID: 388115, updated on 5-Mar-2024

Summary

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Official Symbol
CCDC9Bprovided by HGNC
Official Full Name
coiled-coil domain containing 9Bprovided by HGNC
Primary source
HGNC:HGNC:33488
See related
Ensembl:ENSG00000188549 AllianceGenome:HGNC:33488
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C15orf52
Summary
Enables RNA binding activity. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in thyroid (RPKM 12.1), heart (RPKM 11.6) and 24 other tissues See more
Orthologs
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Genomic context

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Location:
15q15.1
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (40331452..40340939, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (38138324..38147811, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (40623653..40633140, complement)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112268152 Neighboring gene ribosomal protein lateral stalk subunit P0 pseudogene 10 Neighboring gene NANOG hESC enhancer GRCh37_chr15:40613053-40613570 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6323 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6324 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6325 Neighboring gene InaF motif containing 2 Neighboring gene Sharpr-MPRA regulatory region 6286 Neighboring gene RNA, 5S ribosomal pseudogene 392 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:40628805-40629323 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:40632233-40633036 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:40635981-40636480 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:40636664-40637261 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:40637262-40637858 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:40646605-40647130 Neighboring gene proline, histidine and glycine rich 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6328 Neighboring gene uncharacterized LOC124903472 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:40655530-40656030 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:40656031-40656531 Neighboring gene dispatched RND transporter family member 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:40659527-40660418 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6330

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma. Freire-Benéitez V, et al. NAR Cancer, 2021 Mar. PMID 34316702, Free PMC Article
  2. ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Jain S, et al. Cell, 2016 Jan 28. PMID 26777405, Free PMC Article
  3. A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation. Gonzalez Quesada Y, et al. Int J Mol Sci, 2022 Sep 30. PMID 36232890, Free PMC Article
  4. Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma. Mahlokozera T, et al. Nat Commun, 2021 Nov 3. PMID 34732716, Free PMC Article
  5. Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers. Rosenbluh J, et al. Cell Syst, 2016 Sep 28. PMID 27684187, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • FLJ43339, DKFZp686N1468

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding HDA PubMed 

General protein information

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Preferred Names
coiled-coil domain-containing protein 9B
Names
uncharacterized protein C15orf52

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_207380.3 → NP_997263.3  coiled-coil domain-containing protein 9B

    Status: VALIDATED

    Source sequence(s)
    AC013356
    Consensus CDS
    CCDS10055.3
    UniProtKB/Swiss-Prot
    B9EIQ8, Q68DG9, Q6ZTM3, Q6ZU22, Q6ZUT6
    Related
    ENSP00000380670.3, ENST00000397536.7
    Conserved Domains (1) summary
    pfam15266
    Location:139 → 305
    DUF4594; Domain of unknown function (DUF4594)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    40331452..40340939 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    38138324..38147811 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6ZUT6.1 GenPept UniProtKB/Swiss-Prot:Q6ZUT6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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