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HCRP1 hepatocellular carcinoma-related HCRP1 [ Homo sapiens (human) ]

Gene ID: 387535, discontinued on 30-Mar-2017
  • This record has been withdrawn by NCBI staff. This record represented a gene that is not currently annotated by NCBI.

Summary

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Gene symbol
HCRP1
Gene description
hepatocellular carcinoma-related HCRP1
Gene type
unknown
RefSeq status
WITHDRAWN
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
DISCONTINUED: This record has been withdrawn by NCBI staff. This record represented a gene that is not currently annotated by NCBI.

Genomic context

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Location:
6p21.1
Exon count:
1
Sequence:
Chromosome: 6; NC_000006.11 (42326762..42326920)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000006.11 chromosome

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. downregulation of HCRP1 is a valuable prognostic factor involved in EGFR regulation and acquisition of the mesenchymal phenotype of hepatocellular carcinoma cells.
    Title: HCRP1 downregulation promotes hepatocellular carcinoma cell migration and invasion through the induction of EGFR activation and epithelial-mesenchymal transition.
  2. In summary, our results showed that negative HCRP-1 expression is an independent prognostic factor for RCC patients.
    Title: HCRP-1 regulates cell migration and invasion via EGFR-ERK mediated up-regulation of MMP-2 with prognostic significance in human renal cell carcinoma.
  3. Our results suggest that HCRP1 may play an important role in EGFR regulation and that its decreased expression is an independent predictor of breast cancer, especially in triple negative breast cancer patients.
    Title: Decreased HCRP1 expression is associated with poor prognosis in breast cancer patients.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Build 37.1 (NOTE: not current)

The following sections contain reference sequences that belong to a specific genome build. Explain

Genome Reference Consortium Human Build 37 (GRCh37), Primary_Assembly

Genomic

  1. NC_000006.11 Genome Reference Consortium Human Build 37 (GRCh37), Primary_Assembly

    Range
    42326762..42326920
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001725456.2 → XP_001725508.1  

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.