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Bulli bulli [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38734, updated on 18-Sep-2024

Summary

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Official Symbol
Bulliprovided by FlyBase
Official Full Name
bulliprovided by FlyBase
Primary source
FLYBASE:FBgn0035703
Locus tag
Dmel_CG8270
See related
AllianceGenome:FB:FBgn0035703
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
bulli; CG8270; Dmel\CG8270
Summary
Involved in positive regulation of guanyl-nucleotide exchange factor activity. Part of Mon1-Ccz1 complex. Is expressed in adult head. Orthologous to human RMC1 (regulator of MON1-CCZ1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See Bulli in Genome Data Viewer
Location:
65B3-65B3; 3-17 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6488681..6491210)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6481781..6484310)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45979 Neighboring gene Vacuolar protein sorting 8 Neighboring gene sulfateless

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A trimeric metazoan Rab7 GEF complex is crucial for endocytosis and scavenger function. Dehnen L, et al. J Cell Sci, 2020 Jul 9. PMID 32499409
  2. A conserved and regulated mechanism drives endosomal Rab transition. Langemeyer L, et al. Elife, 2020 May 11. PMID 32391792, Free PMC Article
  3. Toward a comprehensive map of the effectors of rab GTPases. Gillingham AK, et al. Dev Cell, 2014 Nov 10. PMID 25453831, Free PMC Article
  4. Latitudinal clines in gene expression and cis-regulatory element variation in Drosophila melanogaster. Juneja P, et al. BMC Genomics, 2016 Nov 28. PMID 27894253, Free PMC Article
  5. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Arya GH, et al. Chem Senses, 2015 May. PMID 25687947, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor adaptor activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of autophagy IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of autophagy IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of Mon1-Ccz1 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Mon1-Ccz1 complex IEA
Inferred from Electronic Annotation
more info
  
part_of Mon1-Ccz1 complex IPI
Inferred from Physical Interaction
more info
 PubMed 
is_active_in late endosome membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
bulli
Names
Bulli-PB
CG8270-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    6488681..6491210
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_139790.3 → NP_648047.2  bulli [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648047.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    C0HDN5, Q9VRX1
    Conserved Domains (1) summary
    pfam07035
    Location:461 → 616
    Mic1; Colon cancer-associated protein Mic1-like
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VRX1 Q9VRX1

Gene LinkOut

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