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gbgt1l4 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4 [ Danio rerio (zebrafish) ]

Gene ID: 387303, updated on 12-Sep-2024

Summary

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Official Symbol
gbgt1l4provided by ZNC
Official Full Name
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4provided by ZNC
Primary source
ZFIN:ZDB-GENE-031204-4
See related
Ensembl:ENSDARG00000068503 AllianceGenome:ZFIN:ZDB-GENE-031204-4
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
sb:cb1003; zgc:66417
Summary
Predicted to enable glycosyltransferase activity. Predicted to be involved in lipid glycosylation. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus and vesicle. Is expressed in several structures, including EVL; ectoderm; epidermis; pectoral fin musculature; and peripheral olfactory organ. Orthologous to human GBGT1 (globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group)). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See gbgt1l4 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (23788592..23805346, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (23284790..23301582, complement)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137495585 Neighboring gene globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 8 Neighboring gene glycoprotein, alpha-galactosyltransferase 1 pseudogene Neighboring gene globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Early developmental pathology due to cytochrome c oxidase deficiency is revealed by a new zebrafish model. Baden KN, et al. J Biol Chem, 2007 Nov 30. PMID 17761683
  2. Connexin 39.9 protein is necessary for coordinated activation of slow-twitch muscle and normal behavior in zebrafish. Hirata H, et al. J Biol Chem, 2012 Jan 6. PMID 22075003, Free PMC Article
  3. Long-term evolution of the CAZY glycosyltransferase 6 (ABO) gene family from fishes to mammals--a birth-and-death evolution model. Turcot-Dubois AL, et al. Glycobiology, 2007 May. PMID 17298992
  4. The circadian clock regulates autophagy directly through the nuclear hormone receptor Nr1d1/Rev-erbα and indirectly via Cebpb/(C/ebpβ) in zebrafish. Huang G, et al. Autophagy, 2016 Aug 2. PMID 27171500, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables glycosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables hexosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in lipid glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4
Names
3-galctosyltransferase
FS-L4
alpha 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200125.1 → NP_956419.1  globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4

    See identical proteins and their annotated locations for NP_956419.1

    Status: PROVISIONAL

    Source sequence(s)
    BC055647
    UniProtKB/TrEMBL
    Q7SXD8
    Related
    ENSDARP00000089858.4, ENSDART00000099084.6
    Conserved Domains (1) summary
    cl11394
    Location:79 → 346
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    23788592..23805346 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005165128.5 → XP_005165185.1  globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4 isoform X1

    UniProtKB/TrEMBL
    A0A8M2BCB7
    Related
    ENSDARP00000120652.1, ENSDART00000133805.2
    Conserved Domains (1) summary
    cl11394
    Location:73 → 340
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

  2. XM_005165129.5 → XP_005165186.1  globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4 isoform X2

    UniProtKB/TrEMBL
    A0A8M2BCH3, A2CED5
    Related
    ENSDARP00000116300.1, ENSDART00000134184.3
    Conserved Domains (1) summary
    cl11394
    Location:72 → 339
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold
Nucleotide Protein
Heading Accession and Version

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