zhx3b zinc fingers and homeoboxes 3b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: zhx3bprovided by ZNC
Official Full Name: zinc fingers and homeoboxes 3bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-031107-1
See related: Ensembl:ENSDARG00000019774 AllianceGenome:ZFIN:ZDB-GENE-031107-1
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: tix1; zhx3; zgc:110489
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in telencephalon. Orthologous to human ZHX3 (zinc fingers and homeoboxes 3). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 23

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	23	NC_007134.7 (2872855..2900839, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	23	NC_007134.6 (2929163..2957268, complement)

Chromosome 23 - NC_007134.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fk95g06.x1 (e-PCR)
- UniSTS:201784

fb93h08.y1 (e-PCR)
- UniSTS:191808

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: zinc fingers and homeoboxes protein 3

Names: triple homeobox 1; zinc fingers and homeoboxes 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_198813.1 → NP_942108.1 zinc fingers and homeoboxes protein 3

See identical proteins and their annotated locations for NP_942108.1

Status: PROVISIONAL

Source sequence(s)

AY311506

UniProtKB/TrEMBL

Q6W5B5

Related

ENSDARP00000005108.5, ENSDART00000022413.6

Conserved Domains (2) summary

smart00389
Location:607 → 660

HOX; Homeodomain

cd00086
Location:895 → 952

homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007134.7 Reference GRCz11 Primary Assembly

Range

2872855..2900839 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009296583.4 → XP_009294858.1 zinc fingers and homeoboxes protein 3 isoform X2

UniProtKB/TrEMBL

A0A8M3B5V6, F1QQ52

Related

ENSDARP00000141318.1, ENSDART00000165955.2

Conserved Domains (2) summary

smart00389
Location:607 → 660

HOX; Homeodomain

cd00086
Location:895 → 952

homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
XM_009296582.4 → XP_009294857.1 zinc fingers and homeoboxes protein 3 isoform X1

UniProtKB/TrEMBL

A0A8M3AMK8, F1R0G0

Conserved Domains (2) summary

smart00389
Location:607 → 660

HOX; Homeodomain

cd00086
Location:895 → 952

homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.