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tlc secreted frizzled-related protein [ Danio rerio (zebrafish) ]

Gene ID: 386615, updated on 2-Nov-2024

Summary

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Official Symbol
tlcprovided by ZNC
Official Full Name
secreted frizzled-related proteinprovided by ZNC
Primary source
ZFIN:ZDB-GENE-031020-1
See related
AllianceGenome:ZFIN:ZDB-GENE-031020-1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
sfrp
Summary
Is expressed in forebrain neural plate; neural keel; and neural plate. [provided by Alliance of Genome Resources, Nov 2024]
Annotation information
not in current annotation release
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Bibliography

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Related articles in PubMed

  1. Establishment of the telencephalon during gastrulation by local antagonism of Wnt signaling. Houart C, et al. Neuron, 2002 Jul 18. PMID 12160744
  2. Cloning and embryonic expression of five distinct sfrp genes in the zebrafish Danio rerio. Tendeng C, et al. Gene Expr Patterns, 2006 Oct. PMID 16504595
  3. BMP signaling protects telencephalic fate by repressing eye identity and its Cxcr4-dependent morphogenesis. Bielen H, et al. Dev Cell, 2012 Oct 16. PMID 23079599, Free PMC Article
  4. Segregation of telencephalic and eye-field identities inside the zebrafish forebrain territory is controlled by Rx3. Stigloher C, et al. Development, 2006 Aug. PMID 16818451
  5. Inhibition of Wnt/Axin/beta-catenin pathway activity promotes ventral CNS midline tissue to adopt hypothalamic rather than floorplate identity. Kapsimali M, et al. Development, 2004 Dec. PMID 15539488, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General protein information

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Preferred Names
secreted frizzled-related protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198362.1 → NP_938176.1  secreted frizzled-related protein precursor

    See identical proteins and their annotated locations for NP_938176.1

    Status: PROVISIONAL

    Source sequence(s)
    AF520426
    UniProtKB/TrEMBL
    Q8JHC7
    Conserved Domains (2) summary
    cd07453
    Location:26 → 162
    CRD_crescent; Cysteine-rich domain of the crescent protein
    cd03580
    Location:154 → 278
    NTR_Sfrp1_like; NTR domain, Secreted frizzled-related protein (Sfrp) 1-like subfamily; composed of proteins similar to human Sfrp1, Sfrp2 and Sfrp5. Sfrps are soluble proteins containing an NTR domain C-terminal to a cysteine-rich Frizzled domain. They show diverse ...
Nucleotide Protein
Heading Accession and Version

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Research Materials