elavl4.L ELAV like neuron-specific RNA binding protein 4 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: elavl4.L
Official Full Name: ELAV like neuron-specific RNA binding protein 4 L homeolog
Primary source: Xenbase:XB-GENE-948214
Locus tag: XELAEV_18023157mg
See related: EnsemblRapid:ENSXLAG00005033792 AllianceGenome:Xenbase:XB-GENE-948214
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: HuD; elrD; elrD1; elrD2; elavl4
Summary: Predicted to enable RNA binding activity. Predicted to be located in several cellular components, including dendrite; growth cone; and perikaryon. Predicted to be part of ribonucleoprotein complex. Is expressed in ectoderm; nervous system; sensory system; vestibuloauditory system; and visual system. Orthologous to human ELAVL4 (ELAV like RNA binding protein 4). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 4L

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	4L	NC_054377.1 (90837678..90902585)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	4L	NC_030730.1 (85537319..85602060)

Chromosome 4L - NC_054377.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data show that the two elrD transcripts, elrD1 and elrD2, present the same tissue-specific pattern of expression, with distinct developmental regulation.
Title: Regulation and expression of elrD1 and elrD2 transcripts during early Xenopus laevis development.
elrD expression was detected in developing Xenopus retina from stage 26 onwards in the differentiating ganglion cell layer.
Title: Comparison of the expression patterns of five neural RNA binding proteins in the Xenopus retina.

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in axon	IEA Inferred from Electronic Annotation more info
located_in cell projection	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in dendrite	IEA Inferred from Electronic Annotation more info
located_in growth cone	IEA Inferred from Electronic Annotation more info
located_in perikaryon	IEA Inferred from Electronic Annotation more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ELAV-like protein 4

Names: ELAV (embryonic lethal, abnormal vision)-like 4 (Hu antigen D); RNA-binding protein HuD; embryonic lethal, abnormal vision, Drosophila)-like 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001087440.1 → NP_001080909.1 ELAV-like protein 4

See identical proteins and their annotated locations for NP_001080909.1

Status: PROVISIONAL

Source sequence(s)

BC056021

UniProtKB/Swiss-Prot

Q4FZM7, Q7SZT7, Q7ZTQ4, Q91585, Q98TU5

UniProtKB/TrEMBL

A0A974D3L2, A0A974D5J3

Related

ENSXLAP00005100973.1, ENSXLAT00005102941.1

Conserved Domains (4) summary

cd12650
Location:50 → 156

RRM1_Hu; RNA recognition motif 1 in the Hu proteins family

cd12656
Location:314 → 399

RRM3_HuD; RNA recognition motif 3 in vertebrate Hu-antigen D (HuD)

TIGR01661
Location:48 → 399

ELAV_HUD_SF; ELAV/HuD family splicing factor

cl17169
Location:161 → 250

RRM_SF; RNA recognition motif (RRM) superfamily