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GRASLND glycosaminoglycan regulatory associated long non-coding RNA [ Homo sapiens (human) ]

Gene ID: 386597, updated on 10-Oct-2023

Summary

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Official Symbol
GRASLNDprovided by HGNC
Official Full Name
glycosaminoglycan regulatory associated long non-coding RNAprovided by HGNC
Primary source
HGNC:HGNC:30963
See related
Ensembl:ENSG00000228203 AllianceGenome:HGNC:30963
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RNF144A-AS1
Expression
Biased expression in spleen (RPKM 6.3), adrenal (RPKM 3.6) and 3 other tissues See more
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Genomic context

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See GRASLND in Genome Data Viewer
Location:
2p25.1
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (6912276..6918682, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (6933777..6940181, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (7052407..7058813, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11120 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15245 Neighboring gene negative regulator of interferon response Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11121 Neighboring gene cytidine/uridine monophosphate kinase 2 Neighboring gene radical S-adenosyl methionine domain containing 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15246 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15247 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11122 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:7064883-7065296 Neighboring gene ring finger protein 144A Neighboring gene Sharpr-MPRA regulatory region 7309 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr2:7113462-7114661 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:7157299-7157798 Neighboring gene Sharpr-MPRA regulatory region 7427/13434 Neighboring gene Sharpr-MPRA regulatory region 3683 Neighboring gene uncharacterized LOC101929452 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15248 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:7249837-7250336 Neighboring gene uncharacterized LOC124908053 Neighboring gene RN7SK pseudogene 112

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Long non-coding RNA GRASLND enhances chondrogenesis via suppression of the interferon type II signaling pathway. Huynh NP, et al. Elife, 2020 Mar 23. PMID 32202492, Free PMC Article
  2. RNF144A-AS1 promotes the development of glioma cells by targeting miR-665/HMGA1 axis. Tong X, et al. Neurosci Lett, 2021 Nov 20. PMID 34560189
  3. Identification of age- and gender-associated long noncoding RNAs in the human brain with Alzheimer's disease. Cao M, et al. Neurobiol Aging, 2019 Sep. PMID 31280115, Free PMC Article
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. RNF144A-AS1 promotes the development of glioma cells by targeting miR-665/HMGA1 axis.
    Title: RNF144A-AS1 promotes the development of glioma cells by targeting miR-665/HMGA1 axis.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

Other Names

  • RNF144A antisense RNA 1 (non-protein coding)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_033997.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC017076
    Related
    ENST00000418970.7

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    6912276..6918682 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    6933777..6940181 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Chemical Information
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