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PolD2 DNA polymerase delta subunit 2 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38228, updated on 2-Nov-2024

Summary

Official Symbol
PolD2provided by FlyBase
Official Full Name
DNA polymerase delta subunit 2provided by FlyBase
Primary source
FLYBASE:FBgn0027903
Locus tag
Dmel_CG12018
See related
AllianceGenome:FB:FBgn0027903
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
12018; BcDNA:HL03874; CG12018; Dmel\CG12018; Pol31
Summary
Predicted to enable DNA binding activity. Involved in mitotic DNA-templated DNA replication. Located in nucleoplasm. Part of delta DNA polymerase complex. Orthologous to human POLD2 (DNA polymerase delta 2, accessory subunit). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See PolD2 in Genome Data Viewer
Location:
62B4-62B4; 3-1.0 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1775633..1777019)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1775633..1777019)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Dynein heavy chain at 62B Neighboring gene antisense RNA:CR44351 Neighboring gene uncharacterized protein Neighboring gene alpha Spectrin Neighboring gene uncharacterized protein Neighboring gene mitochondrial ribosomal protein L46 Neighboring gene antisense RNA:CR45834

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
 
involved_in DNA strand elongation involved in DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in mitotic DNA-templated DNA replication IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
part_of delta DNA polymerase complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of delta DNA polymerase complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
part_of zeta DNA polymerase complex ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
DNA polymerase delta subunit 2
Names
CG12018-PA
DNA polymerase delta small subunit
DNApol- delta small subunit
Pol31 polymerase delta subunit
PolD2-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    1775633..1777019
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_139402.3NP_647659.1  DNA polymerase delta subunit 2 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_647659.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8MZ80, Q9U9Q3, Q9W088, T2GGB6
    Related
    FBpp0072658
    Conserved Domains (1) summary
    cd07387
    Location:175426
    MPP_PolD2_C; PolD2 (DNA polymerase delta, subunit 2), C-terminal domain