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Zfp229 zinc finger protein 229 [ Mus musculus (house mouse) ]

Gene ID: 381067, updated on 2-Nov-2024

Summary

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Official Symbol
Zfp229provided by MGI
Official Full Name
zinc finger protein 229provided by MGI
Primary source
MGI:MGI:2679295
See related
Ensembl:ENSMUSG00000061544 AllianceGenome:MGI:2679295
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in placenta adult (RPKM 4.7), CNS E14 (RPKM 1.8) and 15 other tissues See more
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Genomic context

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See Zfp229 in Genome Data Viewer
Location:
17 A3.3; 17 11.4 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (21949936..21967950)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (21730955..21748969)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1933 Neighboring gene predicted gene 10509 Neighboring gene zinc finger protein 760 Neighboring gene STARR-seq mESC enhancer starr_42015 Neighboring gene STARR-seq mESC enhancer starr_42017 Neighboring gene zinc finger protein 760 pseudogene Neighboring gene zinc finger protein 820 Neighboring gene predicted gene, 31758

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
  2. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Kim H, et al. Cell, 2018 Dec 13. PMID 30550785, Free PMC Article
  3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 229

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164676.1 → NP_001158148.1  zinc finger protein 229

    Status: VALIDATED

    Source sequence(s)
    AK147958, BC043476
    Consensus CDS
    CCDS49995.1
    UniProtKB/TrEMBL
    E9PWT2
    Related
    ENSMUSP00000065379.8, ENSMUST00000065871.14
    Conserved Domains (3) summary
    smart00349
    Location:13 → 73
    KRAB; krueppel associated box
    COG5048
    Location:338 → 704
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:481 → 501
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    21949936..21967950
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030249864.1 → XP_030105724.1  zinc finger protein 229 isoform X1

    UniProtKB/TrEMBL
    E9PWT2
    Related
    ENSMUSP00000138107.2, ENSMUST00000182603.2
    Conserved Domains (3) summary
    smart00349
    Location:13 → 73
    KRAB; krueppel associated box
    COG5048
    Location:338 → 704
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:481 → 501
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. XM_030249862.1 → XP_030105722.1  zinc finger protein 229 isoform X1

    UniProtKB/TrEMBL
    E9PWT2
    Conserved Domains (3) summary
    smart00349
    Location:13 → 73
    KRAB; krueppel associated box
    COG5048
    Location:338 → 704
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:481 → 501
    ZF_C2H2; C2H2 Zn finger [structural motif]

  3. XM_030249863.2 → XP_030105723.1  zinc finger protein 229 isoform X1

    UniProtKB/TrEMBL
    E9PWT2
    Conserved Domains (3) summary
    smart00349
    Location:13 → 73
    KRAB; krueppel associated box
    COG5048
    Location:338 → 704
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:481 → 501
    ZF_C2H2; C2H2 Zn finger [structural motif]

  4. XM_030249861.2 → XP_030105721.1  zinc finger protein 229 isoform X1

    UniProtKB/TrEMBL
    E9PWT2
    Conserved Domains (3) summary
    smart00349
    Location:13 → 73
    KRAB; krueppel associated box
    COG5048
    Location:338 → 704
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:481 → 501
    ZF_C2H2; C2H2 Zn finger [structural motif]

  5. XM_030249860.2 → XP_030105720.1  zinc finger protein 229 isoform X1

    UniProtKB/TrEMBL
    E9PWT2
    Conserved Domains (3) summary
    smart00349
    Location:13 → 73
    KRAB; krueppel associated box
    COG5048
    Location:338 → 704
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:481 → 501
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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