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Tmem106c transmembrane protein 106C [ Mus musculus (house mouse) ]

Gene ID: 380967, updated on 5-Mar-2024

Summary

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Official Symbol
Tmem106cprovided by MGI
Official Full Name
transmembrane protein 106Cprovided by MGI
Primary source
MGI:MGI:1196384
See related
Ensembl:ENSMUSG00000052369 AllianceGenome:MGI:1196384
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D15Ertd405e
Summary
Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Is expressed in several structures, including brain and retina. Orthologous to human TMEM106C (transmembrane protein 106C). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in genital fat pad adult (RPKM 24.2), bladder adult (RPKM 18.3) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Tmem106c in Genome Data Viewer
Location:
15 F1; 15 53.96 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (97862077..97868158)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (97963177..97970286)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33690 Neighboring gene STARR-seq mESC enhancer starr_39643 Neighboring gene vitamin D (1,25-dihydroxyvitamin D3) receptor Neighboring gene predicted gene, 52171 Neighboring gene STARR-positive B cell enhancer mm9_chr15:97738623-97738923 Neighboring gene collagen, type II, alpha 1 Neighboring gene predicted gene, 46536 Neighboring gene predicted gene, 41395

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Genomic analysis of mouse retinal development. Blackshaw S, et al. PLoS Biol, 2004 Sep. PMID 15226823, Free PMC Article
  2. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
  3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Markers

Homology

Clone Names

  • MGC54819

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transmembrane protein 106C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001252153.2 → NP_001239082.1  transmembrane protein 106C isoform 1

    See identical proteins and their annotated locations for NP_001239082.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AC158787
    Consensus CDS
    CCDS27785.1
    UniProtKB/Swiss-Prot
    Q80VP8
    Related
    ENSMUSP00000154819.2, ENSMUST00000229428.2
    Conserved Domains (1) summary
    pfam07092
    Location:18 → 246
    DUF1356; Protein of unknown function (DUF1356)

  2. NM_001356508.2 → NP_001343437.1  transmembrane protein 106C isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AC158787
    Consensus CDS
    CCDS27785.1
    UniProtKB/Swiss-Prot
    Q80VP8
    Conserved Domains (1) summary
    pfam07092
    Location:18 → 246
    DUF1356; Protein of unknown function (DUF1356)

  3. NM_001416066.1 → NP_001402995.1  transmembrane protein 106C isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC158787
    UniProtKB/Swiss-Prot
    Q80VP8

  4. NM_001416067.1 → NP_001402996.1  transmembrane protein 106C isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC158787
    UniProtKB/Swiss-Prot
    Q80VP8

  5. NM_001416068.1 → NP_001402997.1  transmembrane protein 106C isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC158787
    UniProtKB/Swiss-Prot
    Q80VP8

  6. NM_001416069.1 → NP_001402998.1  transmembrane protein 106C isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC158787
    UniProtKB/Swiss-Prot
    Q80VP8

  7. NM_001416070.1 → NP_001402999.1  transmembrane protein 106C isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC158787
    UniProtKB/Swiss-Prot
    Q80VP8

  8. NM_001416071.1 → NP_001403000.1  transmembrane protein 106C isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC158787

  9. NM_001416072.1 → NP_001403001.1  transmembrane protein 106C isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC158787

  10. NM_001416073.1 → NP_001403002.1  transmembrane protein 106C isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC158787

  11. NM_001416074.1 → NP_001403003.1  transmembrane protein 106C isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC158787

  12. NM_201359.3 → NP_958747.1  transmembrane protein 106C isoform 1

    See identical proteins and their annotated locations for NP_958747.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AC158787
    Consensus CDS
    CCDS27785.1
    UniProtKB/Swiss-Prot
    Q80VP8
    Related
    ENSMUSP00000069764.8, ENSMUST00000064200.9
    Conserved Domains (1) summary
    pfam07092
    Location:18 → 246
    DUF1356; Protein of unknown function (DUF1356)

RNA

  1. NR_183250.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC158787

  2. NR_183251.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC158787

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    97862077..97868158
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006521120.3 → XP_006521183.1  transmembrane protein 106C isoform X1

    See identical proteins and their annotated locations for XP_006521183.1

    UniProtKB/Swiss-Prot
    Q80VP8
    Conserved Domains (1) summary
    pfam07092
    Location:18 → 246
    DUF1356; Protein of unknown function (DUF1356)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q80VP8.1 GenPept UniProtKB/Swiss-Prot:Q80VP8

Gene LinkOut

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