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Sec14l3 SEC14-like lipid binding 3 [ Mus musculus (house mouse) ]

Gene ID: 380683, updated on 2-Nov-2024

Summary

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Official Symbol
Sec14l3provided by MGI
Official Full Name
SEC14-like lipid binding 3provided by MGI
Primary source
MGI:MGI:3617848
See related
Ensembl:ENSMUSG00000054986 AllianceGenome:MGI:3617848
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110069O07Rik
Summary
Predicted to be active in cytoplasm. Orthologous to human SEC14L3 (SEC14 like lipid binding 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward lung adult (RPKM 188.4) See more
Orthologs
human all
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Genomic context

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See Sec14l3 in Genome Data Viewer
Location:
11 A1; 11 2.86 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (4014853..4028990)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (4064853..4078990)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene 11954 Neighboring gene STARR-seq mESC enhancer starr_28368 Neighboring gene SEC14-like lipid binding 4 Neighboring gene predicted gene, 51935 Neighboring gene STARR-seq mESC enhancer starr_28370 Neighboring gene mitochondrial fission process 1 Neighboring gene SEC14-like lipid binding 2 Neighboring gene predicted gene, 51934

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Sec14l3 is specifically expressed in mouse airway ciliated cells. Shan L, et al. Inflammation, 2012 Apr. PMID 21796385
  2. Pulmonary microRNA profiles identify involvement of Creb1 and Sec14l3 in bronchial epithelial changes in allergic asthma. Bartel S, et al. Sci Rep, 2017 Apr 6. PMID 28383034, Free PMC Article
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Creb1/Crtc1-3 and Sec14l3 could be important for early responses of the bronchial epithelium to Th2-stimuli.
    Title: Pulmonary microRNA profiles identify involvement of Creb1 and Sec14l3 in bronchial epithelial changes in allergic asthma.
  2. study demonstrated that the ciliated cells in the lung selectively express Sec14l3 mRNA; levels of the Sec14l3 mRNA correlated with the differentiation of ciliated cells
    Title: Sec14l3 is specifically expressed in mouse airway ciliated cells.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
SEC14-like protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001029937.2 → NP_001025108.1  SEC14-like protein 3

    See identical proteins and their annotated locations for NP_001025108.1

    Status: VALIDATED

    Source sequence(s)
    AK004424, AK136060, AL807395, BC138982
    Consensus CDS
    CCDS24375.1
    UniProtKB/TrEMBL
    Q5SQ27
    Related
    ENSMUSP00000065084.7, ENSMUST00000068322.7
    Conserved Domains (2) summary
    smart00516
    Location:76 → 246
    SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
    smart01100
    Location:13 → 59
    CRAL_TRIO_N; CRAL/TRIO, N-terminal domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    4014853..4028990
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011243730.2 → XP_011242032.1  SEC14-like protein 3 isoform X1

    Conserved Domains (1) summary
    smart00516
    Location:22 → 192
    SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
Nucleotide Protein Strain
Heading Accession and Version

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