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mapre1.L microtubule associated protein RP/EB family member 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 380590, updated on 4-Nov-2024

Summary

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Official Symbol
mapre1.L
Official Full Name
microtubule associated protein RP/EB family member 1 L homeolog
Primary source
Xenbase:XB-GENE-17334525
Locus tag
XELAEV_18043048mg
See related
EnsemblRapid:ENSXLAG00005030647 AllianceGenome:Xenbase:XB-GENE-17334525
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
eb1; mapre1
Summary
Predicted to enable microtubule plus-end binding activity. Predicted to act upstream of or within several processes, including protein localization to microtubule; regulation of microtubule polymerization or depolymerization; and spindle assembly. Predicted to be located in microtubule cytoskeleton. Orthologous to human MAPRE1 (microtubule associated protein RP/EB family member 1). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information
Annotation category: partial on reference assembly
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Genomic context

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See mapre1.L in Genome Data Viewer
Location:
chromosome: 9_10L
Exon count:
8
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10L NC_054387.1 (52191..78819, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10L NC_030740.1 (9747..36567, complement)

Chromosome 9_10L - NC_054387.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121398343 Neighboring gene nucleolar protein 4-like L homeolog Neighboring gene ASXL transcriptional regulator 1 L homeolog Neighboring gene kinesin family member 3B L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC52508

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
  
enables microtubule plus-end binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein localization to microtubule IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of microtubule polymerization or depolymerization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within spindle assembly IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in centrosome IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasmic microtubule IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule organizing center IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule plus-end IEA
Inferred from Electronic Annotation
more info
  
located_in spindle midzone IEA
Inferred from Electronic Annotation
more info
  
located_in spindle pole IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
microtubule associated protein RP/EB family member 1 L homeolog
Names
microtubule-associated protein, RP/EB family, member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001087427.1 → NP_001080896.1  microtubule associated protein RP/EB family member 1 L homeolog

    See identical proteins and their annotated locations for NP_001080896.1

    Status: PROVISIONAL

    Source sequence(s)
    AB067727
    UniProtKB/TrEMBL
    A0A974BVY4, A0A974BWX4, Q8UW78
    Related
    ENSXLAP00005091991.1, ENSXLAT00005093672.1
    Conserved Domains (3) summary
    pfam00307
    Location:16 → 114
    CH; Calponin homology (CH) domain
    pfam03271
    Location:238 → 275
    EB1; EB1-like C-terminal motif
    cl21462
    Location:217 → 249
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054387.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    52191..78819 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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