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cela2a.L chymotrypsin like elastase 2A L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 380555, updated on 4-Nov-2024

Summary

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Official Symbol
cela2a.L
Official Full Name
chymotrypsin like elastase 2A L homeolog
Primary source
Xenbase:XB-GENE-970282
Locus tag
XELAEV_18036442mg
See related
EnsemblRapid:ENSXLAG00005015603 AllianceGenome:Xenbase:XB-GENE-970282
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
PE2; ela2; ela2a; cela2a
Summary
Human ortholog(s) of this gene implicated in abdominal obesity-metabolic syndrome 4. Orthologous to human CELA2A (chymotrypsin like elastase 2A). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See cela2a.L in Genome Data Viewer
Location:
chromosome: 7L
Exon count:
8
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 7L NC_054383.1 (135614818..135621342, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 7L NC_030736.1 (121827386..121833914)

Chromosome 7L - NC_054383.1Genomic Context describing neighboring genes Neighboring gene potassium-transporting ATPase alpha chain 1 Neighboring gene transmembrane protein 147 L homeolog Neighboring gene chymotrypsin-like elastase family member 2A Neighboring gene chymotrypsin C L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Screening for novel pancreatic genes from in vitro-induced pancreas in Xenopus. Sogame A, et al. Dev Growth Differ, 2003 Apr. PMID 12752502
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC64568

General protein information

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Preferred Names
chymotrypsin-like elastase family member 2A
Names
chymotrypsin like elastase family member 2A L homeolog
chymotrypsin-like elastase family, member 2A
elastase 2
pancreatic elastase 2
XP_041425776.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054383.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    135614818..135621342 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041569842.1 → XP_041425776.1  chymotrypsin-like elastase family member 2A

    UniProtKB/TrEMBL
    A0A1L8FPG3, A0A974CHH9, Q7SYQ8
    Related
    ENSXLAP00005045834.1, ENSXLAT00005046933.1
    Conserved Domains (1) summary
    cd00190
    Location:29 → 265
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001087392.1: Suppressed sequence

    Description
    NM_001087392.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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