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rbm22.S RNA binding motif protein 22 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 380469, updated on 4-Nov-2024

Summary

Official Symbol
rbm22.S
Official Full Name
RNA binding motif protein 22 S homeolog
Primary source
Xenbase:XB-GENE-971204
Locus tag
XELAEV_18033404mg
See related
EnsemblRapid:ENSXLAG00005004850 AllianceGenome:Xenbase:XB-GENE-971204
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
rbm22; cg14641
Summary
Predicted to enable U6 snRNA binding activity and pre-mRNA binding activity. Predicted to act upstream of or within mRNA cis splicing, via spliceosome and positive regulation of RNA splicing. Predicted to be located in cytoplasm and nucleus. Predicted to be part of Prp19 complex; U2-type catalytic step 1 spliceosome; and U2-type catalytic step 2 spliceosome. Orthologous to human RBM22 (RNA binding motif protein 22). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See rbm22.S in Genome Data Viewer
Location:
chromosome: 6S
Exon count:
12
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 6S NC_054382.1 (75175115..75188573, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 6S NC_030735.1 (63813589..63826924)

Chromosome 6S - NC_054382.1Genomic Context describing neighboring genes Neighboring gene ras responsive element binding protein 1 S homeolog Neighboring gene signal sequence receptor, alpha (translocon-associated protein alpha) S homeolog Neighboring gene RIO kinase 1 S homeolog Neighboring gene desmoplakin S homeolog Neighboring gene collagen alpha-1(IX) chain

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Clone Names

  • MGC53757

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables U6 snRNA binding IEA
Inferred from Electronic Annotation
more info
 
enables U6 snRNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables pre-mRNA binding IEA
Inferred from Electronic Annotation
more info
 
enables pre-mRNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within RNA splicing IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within mRNA cis splicing, via spliceosome ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within positive regulation of RNA splicing ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
part_of Prp19 complex IEA
Inferred from Electronic Annotation
more info
 
part_of U2-type catalytic step 1 spliceosome IEA
Inferred from Electronic Annotation
more info
 
part_of U2-type catalytic step 2 spliceosome IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of spliceosomal complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
pre-mRNA-splicing factor RBM22
Names
RNA-binding motif protein 22

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001087307.1NP_001080776.1  pre-mRNA-splicing factor RBM22

    See identical proteins and their annotated locations for NP_001080776.1

    Status: PROVISIONAL

    Source sequence(s)
    BC045067
    UniProtKB/Swiss-Prot
    Q7ZXB5
    UniProtKB/TrEMBL
    A0A974CKB3
    Related
    ENSXLAP00005014474.1, ENSXLAT00005014670.1
    Conserved Domains (3) summary
    smart00356
    Location:159185
    ZnF_C3H1; zinc finger
    COG0724
    Location:214327
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12224
    Location:231304
    RRM_RBM22; RNA recognition motif (RRM) found in Pre-mRNA-splicing factor RBM22 and similar proteins

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054382.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    75175115..75188573 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041567082.1XP_041423016.1  pre-mRNA-splicing factor RBM22 isoform X1

    UniProtKB/TrEMBL
    A0A8J1L0D7
    Related
    ENSXLAP00005014471.1, ENSXLAT00005014667.1
    Conserved Domains (3) summary
    TIGR01628
    Location:234377
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    smart00356
    Location:159185
    ZnF_C3H1; zinc finger
    smart00360
    Location:233300
    RRM; RNA recognition motif