srsf2.L serine/arginine-rich splicing factor 2 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: srsf2.L
Official Full Name: serine/arginine-rich splicing factor 2 L homeolog
Primary source: Xenbase:XB-GENE-481129
Locus tag: XELAEV_18044106mg
See related: EnsemblRapid:ENSXLAG00005024175 AllianceGenome:Xenbase:XB-GENE-481129
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: sc35; pr264; sc-35; sfrs2; srsf2; sfrs2a; srp30b
Summary: Predicted to enable RNA binding activity. Human ortholog(s) of this gene implicated in acute myeloid leukemia; congestive heart failure; hepatocellular carcinoma; and myelodysplastic syndrome. Orthologous to human SRSF2 (serine and arginine rich splicing factor 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 9_10L

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	9_10L	NC_054387.1 (48166613..48170731, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	9_10L	NC_030740.1 (37849526..37853647, complement)

Chromosome 9_10L - NC_054387.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: serine/arginine-rich splicing factor 2 L homeolog

Names: splicing factor, arginine/serine-rich 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001087274.1 → NP_001080743.1 serine/arginine-rich splicing factor 2 L homeolog

See identical proteins and their annotated locations for NP_001080743.1

Status: PROVISIONAL

Source sequence(s)

BC045229

UniProtKB/TrEMBL

A0A974BYH2, Q7ZX57

Conserved Domains (2) summary

COG0724
Location:5 → 91

RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

cd12311
Location:16 → 88

RRM_SRSF2_SRSF8; RNA recognition motif in serine/arginine-rich splicing factor SRSF2, SRSF8 and similar proteins

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054387.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

48166613..48170731 complement

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GenBank, FASTA, Sequence Viewer (Graphics)