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tes.L testin LIM domain protein L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 380398, updated on 4-Nov-2024

Summary

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Official Symbol
tes.L
Official Full Name
testin LIM domain protein L homeolog
Primary source
Xenbase:XB-GENE-6253774
Locus tag
XELAEV_18017635mg
See related
EnsemblRapid:ENSXLAG00005026178 AllianceGenome:Xenbase:XB-GENE-6253774
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
tes; tess; tess-2
Summary
Predicted to enable zinc ion binding activity. Acts upstream of or within neural crest cell migration. Located in cell cortex. Is expressed in ectoderm; nervous system; sensory system; and vestibuloauditory system. Orthologous to human TES (testin LIM domain protein). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See tes.L in Genome Data Viewer
Location:
chromosome: 3L
Exon count:
7
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (74607803..74625062)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3L NC_030728.1 (59288822..59308094)

Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene cytochrome c oxidase assembly factor 5-like Neighboring gene transcription factor EC L homeolog Neighboring gene caveolin 2 L homeolog Neighboring gene caveolin 1 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Tes regulates neural crest migration and axial elongation in Xenopus. Dingwell KS, et al. Dev Biol, 2006 May 1. PMID 16554046
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Prickle and tes act together to control axial elongation.
    Title: Tes regulates neural crest migration and axial elongation in Xenopus.
Submit: New GeneRIF Correction

General gene information

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Homology

Clone Names

  • MGC53173

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within neural crest cell migration IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in anchoring junction IEA
Inferred from Electronic Annotation
more info
  
located_in cell cortex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
testin
Names
testis derived transcript (3 LIM domains)
xtes

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    74607803..74625062
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041586399.1 → XP_041442333.1  testin

    UniProtKB/Swiss-Prot
    Q7ZXE9
    UniProtKB/TrEMBL
    A0A1L8GYW8, A0A974DDI7
    Related
    ENSXLAP00005077895.1, ENSXLAT00005079486.1
    Conserved Domains (4) summary
    cd09413
    Location:236 → 293
    LIM1_Testin; The first LIM domain of Testin
    cd09416
    Location:299 → 354
    LIM2_Testin; The second LIM domain of Testin
    cd09419
    Location:361 → 419
    LIM3_Testin; The third LIM domain of Testin
    cd09829
    Location:109 → 195
    PET_testin; The PET domain of Testin

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001087237.1: Suppressed sequence

    Description
    NM_001087237.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7ZXE9.1 GenPept UniProtKB/Swiss-Prot:Q7ZXE9

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