rad51.L RAD51 recombinase L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: rad51.L
Official Full Name: RAD51 recombinase L homeolog
Primary source: Xenbase:XB-GENE-6256559
Locus tag: XELAEV_18040067mg
See related: EnsemblRapid:ENSXLAG00005019142
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: reca; brcc5; rad51; rad51a; xrad51; rad51-2; rad51-a; rad51-b; rad51.2
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Genomic context

Location:: chromosome: 8L

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	8L	NC_054385.1 (108280480..108295509)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	8L	NC_030738.1 (93514631..93529623)

Chromosome 8L - NC_054385.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

subunit-subunit interface; Rad51 forms filaments by subunit-subunit contact much like RecA does
Title: Identification of the subunit-subunit interface of Xenopus Rad51.1 protein: similarity to RecA.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables ATP-dependent DNA damage sensor activity	IEA Inferred from Electronic Annotation more info
enables ATP-dependent activity, acting on DNA	IEA Inferred from Electronic Annotation more info
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA strand exchange activity	IEA Inferred from Electronic Annotation more info
enables double-stranded DNA binding	IEA Inferred from Electronic Annotation more info
enables double-stranded DNA binding	ISS Inferred from Sequence or Structural Similarity more info
enables single-stranded DNA binding	IEA Inferred from Electronic Annotation more info
enables single-stranded DNA binding	ISS Inferred from Sequence or Structural Similarity more info
enables single-stranded DNA helicase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA damage response	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within DNA recombinase assembly	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within DNA recombinase assembly	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within DNA repair	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within DNA strand invasion	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within chromosome organization involved in meiotic cell cycle	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within double-strand break repair via homologous recombination	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within double-strand break repair via homologous recombination	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within mitotic recombination	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mitotic recombination-dependent replication fork processing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within reciprocal meiotic recombination	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in chromosome	IEA Inferred from Electronic Annotation more info
located_in chromosome	ISS Inferred from Sequence or Structural Similarity more info
located_in condensed nuclear chromosome	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in nuclear chromosome	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: DNA repair protein RAD51 homolog B

Names: RAD51 homolog (RecA homolog); xRAD51.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001087090.1 → NP_001080559.1 DNA repair protein RAD51 homolog B

See identical proteins and their annotated locations for NP_001080559.1

Status: PROVISIONAL

Source sequence(s)

BC046650

UniProtKB/Swiss-Prot

Q5D0A9, Q91917

UniProtKB/TrEMBL

A0A974H8Y7

Related

ENSXLAP00005056509.1, ENSXLAT00005057746.1

Conserved Domains (3) summary

cd01123
Location:99 → 332

Rad51_DMC1_radA; Rad51_DMC1_radA,B. This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal proteins radA and radB. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a ...

TIGR02239
Location:22 → 336

recomb_RAD51; DNA repair protein RAD51

pfam14520
Location:29 → 77

HHH_5; Helix-hairpin-helix domain