csnk1a1.S casein kinase 1 alpha 1 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: csnk1a1.S
Official Full Name: casein kinase 1 alpha 1 S homeolog
Primary source: Xenbase:XB-GENE-17345862
Locus tag: XELAEV_18021437mg
See related: EnsemblRapid:ENSXLAG00005012982 AllianceGenome:Xenbase:XB-GENE-17345862
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: ck1; csnk1a1
Summary: Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to act upstream of or within negative regulation of canonical Wnt signaling pathway; peptidyl-serine phosphorylation; and signal transduction. Predicted to be located in cytoplasm and nucleus. Orthologous to human CSNK1A1 (casein kinase 1 alpha 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 3S

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	3S	NC_054376.1 (106664314..106702040, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	3S	NC_030729.1 (104757705..104795526, complement)

Chromosome 3S - NC_054376.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables protein kinase activity	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within negative regulation of canonical Wnt signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within peptidyl-serine phosphorylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein phosphorylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: casein kinase 1 alpha 1 S homeolog

Names: casein kinase 1, alpha 1; ck1 alpha

NP_001080546.1

EC 2.7.1.-

XP_018109561.1

EC 2.7.1.-

XP_018109562.1

EC 2.7.1.-

XP_018109563.1

EC 2.7.1.-

XP_041443438.1

EC 2.7.1.-

XP_041443439.1

EC 2.7.1.-

XP_041443440.1

EC 2.7.1.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001087077.1 → NP_001080546.1 casein kinase 1 alpha 1 S homeolog

See identical proteins and their annotated locations for NP_001080546.1

Status: PROVISIONAL

Source sequence(s)

BC043956

UniProtKB/TrEMBL

A0A974HRN9, Q7ZY65

Related

ENSXLAP00005038284.1, ENSXLAT00005039197.1

Conserved Domains (2) summary

COG0515
Location:16 → 239

SPS1; Serine/threonine protein kinase [Signal transduction mechanisms]

cd14128
Location:16 → 281

STKc_CK1_alpha; Catalytic domain of the Serine/Threonine protein kinases, Casein Kinase 1 alpha

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054376.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

106664314..106702040 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041587505.1 → XP_041443439.1 casein kinase 1 alpha 1 S homeolog isoform X4

UniProtKB/TrEMBL

A0A8J1MNS6

Conserved Domains (1) summary

cd14128
Location:16 → 312

STKc_CK1_alpha; Catalytic domain of the Serine/Threonine protein kinases, Casein Kinase 1 alpha
XM_041587504.1 → XP_041443438.1 casein kinase 1 alpha 1 S homeolog isoform X1

UniProtKB/TrEMBL

A0A8J1MPV6

Conserved Domains (1) summary

cd14128
Location:16 → 312

STKc_CK1_alpha; Catalytic domain of the Serine/Threonine protein kinases, Casein Kinase 1 alpha
XM_018254074.2 → XP_018109563.1 casein kinase 1 alpha 1 S homeolog isoform X5

UniProtKB/TrEMBL

A0A8J0UXI6
XM_018254072.2 → XP_018109561.1 casein kinase 1 alpha 1 S homeolog isoform X2

UniProtKB/TrEMBL

A0A1L8GV61, A0A974HRU9

Related

ENSXLAP00005038267.1, ENSXLAT00005039180.1
XM_041587506.1 → XP_041443440.1 casein kinase 1 alpha 1 S homeolog isoform X6

UniProtKB/TrEMBL

A0A8J1MQX7

Conserved Domains (1) summary

cd14128
Location:16 → 284

STKc_CK1_alpha; Catalytic domain of the Serine/Threonine protein kinases, Casein Kinase 1 alpha
XM_018254073.2 → XP_018109562.1 casein kinase 1 alpha 1 S homeolog isoform X3

UniProtKB/TrEMBL

A0A8J0UU78

Related

ENSXLAP00005038255.1, ENSXLAT00005039168.1