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prpsap1.S phosphoribosyl pyrophosphate synthetase-associated protein 1 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 380233, updated on 4-Nov-2024

Summary

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Official Symbol
prpsap1.S
Official Full Name
phosphoribosyl pyrophosphate synthetase-associated protein 1 S homeolog
Primary source
Xenbase:XB-GENE-6486609
Locus tag
XELAEV_18046724mg
See related
EnsemblRapid:ENSXLAG00005017139 AllianceGenome:Xenbase:XB-GENE-6486609
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
prpsap1; prpsap2; prpsap2.L
Summary
Predicted to enable ATP binding activity; magnesium ion binding activity; and ribose phosphate diphosphokinase activity. Predicted to act upstream of or within 5-phosphoribose 1-diphosphate biosynthetic process and purine nucleotide biosynthetic process. Predicted to be located in cytoplasm and membrane. Predicted to be part of ribose phosphate diphosphokinase complex. Orthologous to human PRPSAP1 (phosphoribosyl pyrophosphate synthetase associated protein 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See prpsap1.S in Genome Data Viewer
Location:
chromosome: 9_10S
Exon count:
14
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10S NC_054388.1 (40760422..40784375, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10S NC_030741.1 (34124372..34148540, complement)

Chromosome 9_10S - NC_054388.1Genomic Context describing neighboring genes Neighboring gene UBA-like domain containing 2 S homeolog Neighboring gene glutamine rich 2 S homeolog Neighboring gene uncharacterized LOC108702821 Neighboring gene ubiquitin conjugating enzyme E2 O S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC53428

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables ribose phosphate diphosphokinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within 5-phosphoribose 1-diphosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within nucleotide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within purine nucleotide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of ribose phosphate diphosphokinase complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
phosphoribosyl pyrophosphate synthetase-associated protein 1 S homeolog
Names
phosphoribosyl pyrophosphate synthetase-associated protein 2 L homeolog
phosphoribosylpyrophosphate synthetase-associated protein (39 kDa)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001087072.1 → NP_001080541.1  phosphoribosyl pyrophosphate synthetase-associated protein 1 S homeolog

    See identical proteins and their annotated locations for NP_001080541.1

    Status: PROVISIONAL

    Source sequence(s)
    BC046264
    UniProtKB/TrEMBL
    A0A974BTN0, Q7ZX14
    Related
    ENSXLAP00005050560.1, ENSXLAT00005051701.1
    Conserved Domains (2) summary
    pfam14572
    Location:194 → 390
    Pribosyl_synth; Phosphoribosyl synthetase-associated domain
    pfam13793
    Location:36 → 153
    Pribosyltran_N; N-terminal domain of ribose phosphate pyrophosphokinase

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    40760422..40784375 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018237254.2 → XP_018092743.1  phosphoribosyl pyrophosphate synthetase-associated protein 1 S homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J1LX05
    Conserved Domains (2) summary
    pfam13793
    Location:9 → 126
    Pribosyltran_N; N-terminal domain of ribose phosphate pyrophosphokinase
    pfam14572
    Location:167 → 363
    Pribosyl_synth; Phosphoribosyl synthetase-associated domain

  2. XM_018237252.2 → XP_018092741.1  phosphoribosyl pyrophosphate synthetase-associated protein 1 S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974BTN0, Q7ZX14
    Conserved Domains (2) summary
    pfam14572
    Location:194 → 390
    Pribosyl_synth; Phosphoribosyl synthetase-associated domain
    pfam13793
    Location:36 → 153
    Pribosyltran_N; N-terminal domain of ribose phosphate pyrophosphokinase

  3. XM_041577652.1 → XP_041433586.1  phosphoribosyl pyrophosphate synthetase-associated protein 1 S homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J1LX05
    Conserved Domains (2) summary
    pfam13793
    Location:9 → 126
    Pribosyltran_N; N-terminal domain of ribose phosphate pyrophosphokinase
    pfam14572
    Location:167 → 363
    Pribosyl_synth; Phosphoribosyl synthetase-associated domain

  4. XM_018237253.2 → XP_018092742.1  phosphoribosyl pyrophosphate synthetase-associated protein 1 S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974BTN0, Q7ZX14
    Conserved Domains (2) summary
    pfam14572
    Location:194 → 390
    Pribosyl_synth; Phosphoribosyl synthetase-associated domain
    pfam13793
    Location:36 → 153
    Pribosyltran_N; N-terminal domain of ribose phosphate pyrophosphokinase

  5. XM_018237251.2 → XP_018092740.1  phosphoribosyl pyrophosphate synthetase-associated protein 1 S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974BTN0, Q7ZX14
    Conserved Domains (2) summary
    pfam14572
    Location:194 → 390
    Pribosyl_synth; Phosphoribosyl synthetase-associated domain
    pfam13793
    Location:36 → 153
    Pribosyltran_N; N-terminal domain of ribose phosphate pyrophosphokinase

  6. XM_041577651.1 → XP_041433585.1  phosphoribosyl pyrophosphate synthetase-associated protein 1 S homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J1LXV2
    Related
    ENSXLAP00005050586.1, ENSXLAT00005051727.1
    Conserved Domains (1) summary
    COG0462
    Location:35 → 377
    PrsA; Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism, Amino acid transport and metabolism]
Nucleotide Protein Strain
Heading Accession and Version

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