ercc1.L excision repair cross-complementation group 1 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: ercc1.L
Official Full Name: excision repair cross-complementation group 1 L homeolog
Primary source: Xenbase:XB-GENE-5895512
Locus tag: XELAEV_18035087mg
See related: EnsemblRapid:ENSXLAG00005029716
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: ercc1
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Genomic context

Location:: chromosome: 7L

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	7L	NC_054383.1 (62141689..62179637)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	7L	NC_030736.1 (54031318..54066002)

Chromosome 7L - NC_054383.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These data support a model in which the interstrand crosslink repair-specific function of XPF-ERCC1 is dependent on recruitment, positioning and substrate recognition.
Title: Recruitment and positioning determine the specific role of the XPF-ERCC1 endonuclease in interstrand crosslink repair.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables damaged DNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA recombination	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within DNA repair	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within double-strand break repair	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: excision repair cross-complementing 1

Names: excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001087029.1 → NP_001080498.1 excision repair cross-complementing 1

See identical proteins and their annotated locations for NP_001080498.1

Status: PROVISIONAL

Source sequence(s)

BC043824

UniProtKB/TrEMBL

A0A974HC57, Q7ZYE2

Conserved Domains (3) summary

COG5241
Location:69 → 280

RAD10; Nucleotide excision repair endonuclease NEF1, RAD10 subunit [DNA replication, recombination, and repair]

pfam03834
Location:99 → 212

Rad10; Binding domain of DNA repair protein Ercc1 (rad10/Swi10)

pfam14520
Location:238 → 286

HHH_5; Helix-hairpin-helix domain