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cadm3.S cell adhesion molecule 3 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 380160, updated on 4-Nov-2024

Summary

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Official Symbol
cadm3.S
Official Full Name
cell adhesion molecule 3 S homeolog
Primary source
Xenbase:XB-GENE-1012968
Locus tag
XELAEV_18042703mg
See related
EnsemblRapid:ENSXLAG00005020959 AllianceGenome:Xenbase:XB-GENE-1012968
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
cadm3; necl1; cadm3.L
Summary
Predicted to act upstream of or within cell adhesion. Predicted to be located in anchoring junction and plasma membrane. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease. Orthologous to human CADM3 (cell adhesion molecule 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cadm3.S in Genome Data Viewer
Location:
chromosome: 8S
Exon count:
10
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8S NC_054386.1 (94299503..94524462)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8S NC_030739.1 (89449642..89676267)

Chromosome 8S - NC_054386.1Genomic Context describing neighboring genes Neighboring gene vomeronasal type-2 receptor 26 Neighboring gene transfer RNA arginine (anticodon UCU) Neighboring gene C-reactive protein-like Neighboring gene MGC86526 protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC52711

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within cell adhesion IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in anchoring junction IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cell adhesion molecule 3
Names
cell adhesion molecule 3 L homeolog
igSF4B
immunoglobulin superfamily member 4B
nectin-lke 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054386.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    94299503..94524462
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041574425.1 → XP_041430359.1  cell adhesion molecule 3 isoform X1

    UniProtKB/TrEMBL
    A0A8J1LMI6, A0A974H692
    Related
    ENSXLAP00005061509.1, ENSXLAT00005062962.1
    Conserved Domains (5) summary
    smart00294
    Location:354 → 372
    4.1m; putative band 4.1 homologues' binding motif
    cd05882
    Location:27 → 121
    IgV_1_Necl-1; First (N-terminal) immunoglobulin (Ig)-like domain of nectin-like molecule-1 (Necl-1); member of the V-set of Ig superfamily (IgSF) domains
    smart00408
    Location:241 → 302
    IGc2; Immunoglobulin C-2 Type
    smart00409
    Location:138 → 206
    IG; Immunoglobulin
    cd00096
    Location:245 → 249
    Ig; Ig strand B [structural motif]

  2. XM_041574426.1 → XP_041430360.1  cell adhesion molecule 3 isoform X2

    UniProtKB/Swiss-Prot
    Q7ZXX1
    UniProtKB/TrEMBL
    A0A8J1LNU7, A0A974H692
    Related
    ENSXLAP00005061520.1, ENSXLAT00005062973.1
    Conserved Domains (5) summary
    smart00294
    Location:347 → 365
    4.1m; putative band 4.1 homologues' binding motif
    cd05882
    Location:27 → 121
    IgV_1_Necl-1; First (N-terminal) immunoglobulin (Ig)-like domain of nectin-like molecule-1 (Necl-1); member of the V-set of Ig superfamily (IgSF) domains
    pfam13927
    Location:227 → 299
    Ig_3; Immunoglobulin domain
    cd00096
    Location:235 → 240
    Ig; Ig strand A' [structural motif]
    cd07705
    Location:122 → 224
    IgI_2_Necl-1; Second immunoglobulin (Ig)-like domain of nectin-like molcule-1 (Necl-1); member of the I-set of Ig superfamily domains

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001086999.1: Suppressed sequence

    Description
    NM_001086999.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7ZXX1.1 GenPept UniProtKB/Swiss-Prot:Q7ZXX1

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