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actl6a.S actin like 6A S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 380143, updated on 4-Nov-2024

Summary

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Official Symbol
actl6a.S
Official Full Name
actin like 6A S homeolog
Primary source
Xenbase:XB-GENE-866110
Locus tag
XELAEV_18029687mg
See related
EnsemblRapid:ENSXLAG00005007693 AllianceGenome:Xenbase:XB-GENE-866110
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
arp4; actin; actl6; actl6a; baf53a; ino80k; actl6a.L; arpn-beta
Summary
Predicted to enable chromatin binding activity. Predicted to act upstream of or within nervous system development and regulation of transcription by RNA polymerase II. Predicted to be part of NuA4 histone acetyltransferase complex and SWI/SNF complex. Orthologous to human ACTL6A (actin like 6A). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See actl6a.S in Genome Data Viewer
Location:
chromosome: 5S
Exon count:
14
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5S NC_054380.1 (95430006..95443898, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5S NC_030733.1 (89659062..89672954, complement)

Chromosome 5S - NC_054380.1Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 13 S homeolog Neighboring gene uncharacterized LOC108717575 Neighboring gene guanine nucleotide binding protein (G protein), beta polypeptide 4 S homeolog Neighboring gene mitofusin 1 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Nuclear actin polymerization is required for transcriptional reprogramming of Oct4 by oocytes. Miyamoto K, et al. Genes Dev, 2011 May 1. PMID 21536734, Free PMC Article
  2. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Kırlı K, et al. Elife, 2015 Dec 17. PMID 26673895, Free PMC Article
  3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC52964

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within nervous system development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of NuA4 histone acetyltransferase complex IEA
Inferred from Electronic Annotation
more info
  
part_of SWI/SNF complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
actin like 6A S homeolog
Names
actin like 6A L homeolog
actin-like 6A
actin-related protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001086982.1 → NP_001080451.1  actin like 6A S homeolog

    See identical proteins and their annotated locations for NP_001080451.1

    Status: PROVISIONAL

    Source sequence(s)
    BC043771
    UniProtKB/TrEMBL
    A0A974CWL3, A0A974HIB3, Q7ZYI5
    Related
    ENSXLAP00005021940.1, ENSXLAT00005022632.1
    Conserved Domains (2) summary
    pfam00022
    Location:11 → 429
    Actin; Actin
    cl17037
    Location:10 → 428
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054380.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    95430006..95443898 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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