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tbl2.L transducin (beta)-like 2 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 380072, updated on 4-Nov-2024

Summary

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Official Symbol
tbl2.L
Official Full Name
transducin (beta)-like 2 L homeolog
Primary source
Xenbase:XB-GENE-5852683
Locus tag
XELAEV_18011645mg
See related
EnsemblRapid:ENSXLAG00005025671 AllianceGenome:Xenbase:XB-GENE-5852683
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
tbl2; cgno01; wbscr13; ws-betatrp
Summary
Predicted to act upstream of or within endoplasmic reticulum unfolded protein response. Predicted to be located in endoplasmic reticulum. Orthologous to human TBL2 (transducin beta like 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See tbl2.L in Genome Data Viewer
Location:
chromosome: 2L
Exon count:
8
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2L NC_054373.1 (29689091..29698910, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2L NC_030726.1 (29417301..29427138, complement)

Chromosome 2L - NC_054373.1Genomic Context describing neighboring genes Neighboring gene polyubiquitin-C Neighboring gene BCL7B, BAF complex component L homeolog Neighboring gene integrin subunit alpha E L homeolog Neighboring gene transient receptor potential cation channel, subfamily V, member 2 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An atlas of differential gene expression during early Xenopus embryogenesis. Pollet N, et al. Mech Dev, 2005 Mar. PMID 15763213
  2. Axeldb: a Xenopus laevis database focusing on gene expression. Pollet N, et al. Nucleic Acids Res, 2000 Jan 1. PMID 10592204, Free PMC Article
  3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC53692

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within endoplasmic reticulum unfolded protein response IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transducin (beta)-like 2 L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001086911.1 → NP_001080380.1  transducin (beta)-like 2 L homeolog

    See identical proteins and their annotated locations for NP_001080380.1

    Status: PROVISIONAL

    Source sequence(s)
    BC043633
    UniProtKB/TrEMBL
    Q3B8J3, Q7ZTQ6
    Related
    ENSXLAP00005076311.1, ENSXLAT00005077900.1
    Conserved Domains (3) summary
    COG2319
    Location:79 → 388
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:86 → 129
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:75 → 388
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054373.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    29689091..29698910 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041580870.1 → XP_041436804.1  transducin (beta)-like 2 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1M542
    Conserved Domains (2) summary
    sd00039
    Location:69 → 111
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:19 → 230
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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