slc25a25.L solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: slc25a25.L
Official Full Name: solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 L homeolog
Primary source: Xenbase:XB-GENE-5933262
Locus tag: XELAEV_18004119mg
See related: EnsemblRapid:ENSXLAG00005020931 AllianceGenome:Xenbase:XB-GENE-5933262
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: mcsc; pcscl; scamc2; scamc-2; slc25a25
Summary: Predicted to enable ATP transmembrane transporter activity and calcium ion binding activity. Predicted to act upstream of or within ADP transport; ATP transport; and transmembrane transport. Predicted to be located in mitochondrial inner membrane. Orthologous to human SLC25A25 (solute carrier family 25 member 25). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 8L

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	8L	NC_054385.1 (15569274..15595806, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	Unplaced Scaffold	NW_016694861.1 (4366..39554)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	Unplaced Scaffold	NW_016701486.1 (752..1094)

Chromosome 8L - NC_054385.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables ATP transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within ADP transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within ATP transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: calcium-binding mitochondrial carrier protein SCaMC-2

Names: mitochondrial Ca2+-dependent solute carrier; small calcium-binding mitochondrial carrier protein 2; solute carrier family 25 member 25

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001086879.1 → NP_001080348.1 calcium-binding mitochondrial carrier protein SCaMC-2

See identical proteins and their annotated locations for NP_001080348.1

Status: PROVISIONAL

Source sequence(s)

BC043834

UniProtKB/Swiss-Prot

Q7ZYD5

Conserved Domains (3) summary

cd00051
Location:127 → 186

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

pfam00153
Location:231 → 319

Mito_carr; Mitochondrial carrier protein

pfam13499
Location:64 → 121

EF-hand_7; EF-hand domain pair

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

15569274..15595806 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041571913.1 → XP_041427847.1 calcium-binding mitochondrial carrier protein SCaMC-2 isoform X1

UniProtKB/TrEMBL

A0A8J1LE90

Related

ENSXLAP00005061457.1, ENSXLAT00005062910.1

Conserved Domains (4) summary

COG5126
Location:59 → 169

FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

PTZ00169
Location:247 → 501

PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

cd15898
Location:127 → 156

EFh_PI-PLC; EF-hand motif [structural motif]

cl28895
Location:127 → 232

EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
XM_041571914.1 → XP_041427848.1 calcium-binding mitochondrial carrier protein SCaMC-2 isoform X2

UniProtKB/TrEMBL

A0A8J1LE81

Conserved Domains (5) summary

PTZ00169
Location:216 → 470

PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

cd15898
Location:96 → 125

EFh_PI-PLC; EF-hand motif [structural motif]

cd15897
Location:67 → 91

EFh_PEF; EF-hand motif [structural motif]

cl28895
Location:96 → 201

EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes

cl25352
Location:67 → 139

EFh_PEF; The penta-EF hand (PEF) family
XM_041571915.1 → XP_041427849.1 calcium-binding mitochondrial carrier protein SCaMC-2 isoform X3

UniProtKB/TrEMBL

A0A8J1LFP9, A0A974BRM4

Related

ENSXLAP00005061436.1, ENSXLAT00005062886.1

Conserved Domains (6) summary

PTZ00169
Location:202 → 456

PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

cd15898
Location:82 → 111

EFh_PI-PLC; EF-hand motif [structural motif]

cd15897
Location:53 → 77

EFh_PEF; EF-hand motif [structural motif]

cl28895
Location:82 → 187

EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes

cl25352
Location:53 → 125

EFh_PEF; The penta-EF hand (PEF) family

cl08302
Location:27 → 74

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
XM_041571916.1 → XP_041427850.1 calcium-binding mitochondrial carrier protein SCaMC-2 isoform X4

UniProtKB/TrEMBL

A0A8J1LGN5, A0A974BRM4

Related

ENSXLAP00005061440.1, ENSXLAT00005062893.1

Conserved Domains (4) summary

PTZ00169
Location:191 → 445

PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

cd15897
Location:53 → 77

EFh_PEF; EF-hand motif [structural motif]

cl25352
Location:53 → 139

EFh_PEF; The penta-EF hand (PEF) family

cl08302
Location:27 → 74

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...