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klf6.L KLF transcription factor 6 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 379949, updated on 4-Nov-2024

Summary

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Official Symbol
klf6.L
Official Full Name
KLF transcription factor 6 L homeolog
Primary source
Xenbase:XB-GENE-6254475
Locus tag
XELAEV_18030713mg
See related
EnsemblRapid:ENSXLAG00005023045 AllianceGenome:Xenbase:XB-GENE-6254475
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
gbf; zf9; bcd1; cba1; cpbp; klf6; pac1; st12; copeb; klf6-a; klf6-b
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Is expressed in anatomical system; ectoderm; and pharyngeal arch. Human ortholog(s) of this gene implicated in prostate cancer and stomach cancer. Orthologous to human KLF6 (KLF transcription factor 6). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See klf6.L in Genome Data Viewer
Location:
chromosome: 6L
Exon count:
4
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 6L NC_054381.1 (19462117..19470003, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 6L NC_030734.1 (16902484..16910399, complement)

Chromosome 6L - NC_054381.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108718754 Neighboring gene pitrilysin metallopeptidase 1 L homeolog Neighboring gene uncharacterized LOC121394854 Neighboring gene frizzled class receptor 8 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC53475

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
KLF transcription factor 6 L homeolog
Names
Kruppel-like factor 6 L homeolog
core promoter element binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001086788.1 → NP_001080257.1  KLF transcription factor 6 L homeolog

    See identical proteins and their annotated locations for NP_001080257.1

    Status: PROVISIONAL

    Source sequence(s)
    BC044713
    UniProtKB/TrEMBL
    A0A974CLQ7, Q7ZXK7
    Related
    ENSXLAP00005067927.1, ENSXLAT00005069461.1
    Conserved Domains (3) summary
    COG5048
    Location:185 → 265
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:205 → 224
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:246 → 271
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054381.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    19462117..19470003 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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