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ptp4a2.S protein tyrosine phosphatase type IVA, member 2 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 379932, updated on 4-Nov-2024

Summary

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Official Symbol
ptp4a2.S
Official Full Name
protein tyrosine phosphatase type IVA, member 2 S homeolog
Primary source
Xenbase:XB-GENE-17335105
Locus tag
XELAEV_18015223mg
See related
EnsemblRapid:ENSXLAG00005003891 AllianceGenome:Xenbase:XB-GENE-17335105
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
hh13; ov-1; prl2; hh7-2; prl-2; ptp4a2; ptp-iv1b; ptpcaax2
Summary
Predicted to enable protein tyrosine phosphatase activity. Predicted to act upstream of or within protein dephosphorylation. Predicted to be located in cytoplasm and nucleus. Orthologous to human PTP4A2 (protein tyrosine phosphatase 4A2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ptp4a2.S in Genome Data Viewer
Location:
chromosome: 2S
Exon count:
8
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2S NC_054374.1 (78207109..78232136)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2S NC_030727.1 (70905674..70930701)

Chromosome 2S - NC_054374.1Genomic Context describing neighboring genes Neighboring gene karyopherin alpha 6 (importin alpha 7) S homeolog Neighboring gene taxilin alpha S homeolog Neighboring gene uncharacterized LOC121400604 Neighboring gene adhesion G protein-coupled receptor B2 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC53390

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein tyrosine phosphatase type IVA, member 2 S homeolog
Names
protein tyrosine phosphatase 4a2
NP_001080240.1
XP_018103530.1
XP_018103532.1
XP_018103533.1
XP_018103534.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001086771.1 → NP_001080240.1  protein tyrosine phosphatase type IVA, member 2 S homeolog

    See identical proteins and their annotated locations for NP_001080240.1

    Status: PROVISIONAL

    Source sequence(s)
    BC044707
    UniProtKB/TrEMBL
    A0A974DHM4, Q7ZXL1
    Related
    ENSXLAP00005011638.1, ENSXLAT00005011812.1
    Conserved Domains (1) summary
    cl21483
    Location:8 → 157
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054374.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    78207109..78232136
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018248041.2 → XP_018103530.1  protein tyrosine phosphatase type IVA, member 2 S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974DHM4, Q7ZXL1

  2. XM_018248043.2 → XP_018103532.1  protein tyrosine phosphatase type IVA, member 2 S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974DHM4, Q7ZXL1

  3. XM_018248044.2 → XP_018103533.1  protein tyrosine phosphatase type IVA, member 2 S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974DHM4, Q7ZXL1

  4. XM_018248045.2 → XP_018103534.1  protein tyrosine phosphatase type IVA, member 2 S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974DHM4, Q7ZXL1
Nucleotide Protein Strain
Heading Accession and Version

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