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atp1b1.S ATPase Na+/K+ transporting subunit beta 1 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 379920, updated on 4-Nov-2024

Summary

Official Symbol
atp1b1.S
Official Full Name
ATPase Na+/K+ transporting subunit beta 1 S homeolog
Primary source
Xenbase:XB-GENE-864911
Locus tag
XELAEV_18014713mg
See related
EnsemblRapid:ENSXLAG00005032613 AllianceGenome:Xenbase:XB-GENE-864911
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
atp1b1; atp1b1a
Summary
Enables ATPase activator activity and protein-macromolecule adaptor activity. Acts upstream of or within intracellular monoatomic cation homeostasis; membrane repolarization; and monoatomic cation transmembrane transport. Part of sodium:potassium-exchanging ATPase complex. Is expressed in anatomical system and primary germ layer. Human ortholog(s) of this gene implicated in essential hypertension. Orthologous to human ATP1B1 (ATPase Na+/K+ transporting subunit beta 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See atp1b1.S in Genome Data Viewer
Location:
chromosome: 2S
Exon count:
6
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2S NC_054374.1 (47146798..47161125)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2S NC_030727.1 (44308645..44322972)

Chromosome 2S - NC_054374.1Genomic Context describing neighboring genes Neighboring gene dermatopontin S homeolog Neighboring gene coiled-coil domain-containing protein 80-like Neighboring gene NME/NM23 family member 7 S homeolog Neighboring gene basic leucine zipper nuclear factor 1 S homeolog Neighboring gene coiled-coil domain containing 181 S homeolog

Genomic regions, transcripts, and products

General gene information

Clone Names

  • MGC52581

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATPase activator activity IDA
Inferred from Direct Assay
more info
PubMed 
enables ATPase activator activity IEA
Inferred from Electronic Annotation
more info
 
enables protein-macromolecule adaptor activity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
part_of sodium:potassium-exchanging ATPase complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of sodium:potassium-exchanging ATPase complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ATPase Na+/K+ transporting subunit beta 1 S homeolog
Names
ATPase, Na+/K+ transporting, beta 1 polypeptide S homeolog
ATPase, Na+/K+ transporting, beta 1a polypeptide
Beta1-Na/K-ATPase
Na+-K+-ATPase

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001086759.1NP_001080228.1  ATPase Na+/K+ transporting subunit beta 1 S homeolog

    See identical proteins and their annotated locations for NP_001080228.1

    Status: PROVISIONAL

    Source sequence(s)
    BC047957
    UniProtKB/TrEMBL
    A0A974HVA1, Q91580
    Related
    ENSXLAP00005097685.1, ENSXLAT00005099489.1
    Conserved Domains (1) summary
    TIGR01107
    Location:1303
    Na_K_ATPase_bet; Sodium Potassium ATPase beta subunit

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054374.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    47146798..47161125
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)