api5.S apoptosis inhibitor 5 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: api5.S
Official Full Name: apoptosis inhibitor 5 S homeolog
Primary source: Xenbase:XB-GENE-963042
Locus tag: XELAEV_18024539mg
See related: EnsemblRapid:ENSXLAG00005023750 AllianceGenome:Xenbase:XB-GENE-963042
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: api5; aac11; API-5B; aac-11; api5-a; api5-b; sr:nyz021
Summary: Predicted to enable fibroblast growth factor binding activity. Predicted to act upstream of or within negative regulation of apoptotic process. Predicted to be located in nucleus. Orthologous to human API5 (apoptosis inhibitor 5). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 4S

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	4S	NC_054378.1 (16835918..16860571, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	4S	NC_030731.1 (16244175..16269080, complement)

Chromosome 4S - NC_054378.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables fibroblast growth factor binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within apoptotic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within negative regulation of apoptotic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within negative regulation of apoptotic process	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: apoptosis inhibitor 5-B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001086757.1 → NP_001080226.1 apoptosis inhibitor 5-B

See identical proteins and their annotated locations for NP_001080226.1

Status: PROVISIONAL

Source sequence(s)

BC043906

UniProtKB/Swiss-Prot

Q7ZY79

UniProtKB/TrEMBL

A0A974D0M1, A0A974D147

Related

ENSXLAP00005070375.1, ENSXLAT00005071915.1

Conserved Domains (3) summary

pfam05918
Location:4 → 496

API5; Apoptosis inhibitory protein 5 (API5)

pfam13646
Location:70 → 156

HEAT_2; HEAT repeats

sd00044
Location:63 → 91

HEAT; HEAT repeat [structural motif]

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054378.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

16835918..16860571 complement

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GenBank, FASTA, Sequence Viewer (Graphics)