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cacybp.S calcyclin binding protein S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 379906, updated on 4-Nov-2024

Summary

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Official Symbol
cacybp.S
Official Full Name
calcyclin binding protein S homeolog
Primary source
Xenbase:XB-GENE-17340971
Locus tag
XELAEV_18025315mg
See related
EnsemblRapid:ENSXLAG00005022465 AllianceGenome:Xenbase:XB-GENE-17340971
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
sip; gig5
Summary
Predicted to enable S100 protein binding activity; tubulin binding activity; and ubiquitin protein ligase binding activity. Predicted to act upstream of or within heart development. Predicted to be located in cytoplasm and nucleus. Orthologous to human CACYBP (calcyclin binding protein). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information
Annotation category: partial on reference assembly
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Genomic context

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See cacybp.S in Genome Data Viewer
Location:
chromosome: 4S
Exon count:
7
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4S NC_054378.1 (77837123..77843936)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4S NC_030731.1 (71633376..71640208)

Chromosome 4S - NC_054378.1Genomic Context describing neighboring genes Neighboring gene Xetrov90011961m S homeolog Neighboring gene small nucleolar RNA snR60/Z15/Z230/Z193/J17 Neighboring gene small nucleolar RNA snR60/Z15/Z230/Z193/J17 Neighboring gene mitochondrial ribosomal protein S14 S homeolog Neighboring gene uncharacterized LOC121393319

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC53235

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables S100 protein binding IEA
Inferred from Electronic Annotation
more info
  
enables tubulin binding IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin protein ligase binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within heart development IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
calcyclin binding protein S homeolog
Names
Siah-interacting protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001086745.1 → NP_001080214.1  calcyclin binding protein S homeolog

    See identical proteins and their annotated locations for NP_001080214.1

    Status: PROVISIONAL

    Source sequence(s)
    BC046706
    UniProtKB/TrEMBL
    A0A974D1U3, Q7ZWU4
    Related
    ENSXLAP00005066061.1, ENSXLAT00005067584.1
    Conserved Domains (2) summary
    cd06468
    Location:74 → 165
    p23_CacyBP; p23_like domain found in proteins similar to Calcyclin-Binding Protein(CacyBP)/Siah-1-interacting protein (SIP). CacyBP/SIP interacts with S100A6 (calcyclin), with some other members of the S100 family, with tubulin, and with Siah-1 and Skp-1. The latter ...
    pfam09032
    Location:5 → 74
    Siah-Interact_N; Siah interacting protein, N terminal

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054378.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    77837123..77843936
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials