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hspa9.L heat shock protein family A (Hsp70) member 9 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 379858, updated on 4-Nov-2024

Summary

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Official Symbol
hspa9.L
Official Full Name
heat shock protein family A (Hsp70) member 9 L homeolog
Primary source
Xenbase:XB-GENE-6254680
Locus tag
XELAEV_18016934mg
See related
EnsemblRapid:ENSXLAG00005001607 AllianceGenome:Xenbase:XB-GENE-6254680
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
csa; mot; mot2; grp75; pbp74; grp-75; hspa9b; hspa9-a; hspa9-b; mortalin
Summary
Predicted to enable ATP binding activity; ATP-dependent protein folding chaperone; and unfolded protein binding activity. Predicted to act upstream of or within protein folding. Predicted to be located in mitochondrion. Is expressed in anatomical system; mesenchyme; pharyngeal arch; and primary germ layer. Human ortholog(s) of this gene implicated in Parkinson's disease and autosomal dominant sideroblastic anemia 4. Orthologous to human HSPA9 (heat shock protein family A (Hsp70) member 9). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See hspa9.L in Genome Data Viewer
Location:
chromosome: 3L
Exon count:
19
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (27825771..27851969, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3L NC_030728.1 (14912573..14938800, complement)

Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 23 member 1 L homeolog Neighboring gene nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog Neighboring gene catenin alpha 1 L homeolog Neighboring gene DAP3 binding cell death enhancer 1 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC53528

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP-dependent protein folding chaperone IEA
Inferred from Electronic Annotation
more info
  
enables unfolded protein binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein folding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
heat shock protein family A (Hsp70) member 9 L homeolog
Names
heat shock 70kDa protein 9 (mortalin)
heat shock protein, 74 kDa, A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001086697.1 → NP_001080166.1  heat shock protein family A (Hsp70) member 9 L homeolog

    See identical proteins and their annotated locations for NP_001080166.1

    Status: PROVISIONAL

    Source sequence(s)
    BC045130
    UniProtKB/TrEMBL
    A0A974DBH2, Q7ZX77
    Related
    ENSXLAP00005004808.1, ENSXLAT00005004905.1
    Conserved Domains (1) summary
    PRK00290
    Location:46 → 664
    dnaK; molecular chaperone DnaK; Provisional

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    27825771..27851969 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041584944.1 → XP_041440878.1  heat shock protein family A (Hsp70) member 9 L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J1MH79, A0A974DBH2
    Related
    ENSXLAP00005004809.1, ENSXLAT00005004906.1
    Conserved Domains (1) summary
    PRK00290
    Location:46 → 633
    dnaK; molecular chaperone DnaK; Provisional

  2. XM_041584942.1 → XP_041440876.1  heat shock protein family A (Hsp70) member 9 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974DBH2, Q7ZX77
    Related
    ENSXLAP00005004810.1, ENSXLAT00005004907.1
    Conserved Domains (1) summary
    PRK00290
    Location:46 → 664
    dnaK; molecular chaperone DnaK; Provisional

  3. XM_041584943.1 → XP_041440877.1  heat shock protein family A (Hsp70) member 9 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974DBH2, Q7ZX77
    Conserved Domains (1) summary
    PRK00290
    Location:46 → 664
    dnaK; molecular chaperone DnaK; Provisional
Nucleotide Protein Strain
Heading Accession and Version

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