zmcm3.L Putative ortholog of dNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (RLF beta subunit) (P102 protein) (P1-MCM3), 1 of 1 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: zmcm3.L
Official Full Name: Putative ortholog of dNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (RLF beta subunit) (P102 protein) (P1-MCM3), 1 of 1 L homeolog
Primary source: Xenbase:XB-GENE-971651
Locus tag: XELAEV_18028222mg
See related: EnsemblRapid:ENSXLAG00005009362
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: mcm3
Annotation information: Annotation category: partial on reference assembly
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Genomic context

Location:: chromosome: 5L

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	5L	NC_054379.1 (161941031..161961069, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	5L	NC_030732.1 (150900119..150920157, complement)

Chromosome 5L - NC_054379.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables DNA binding	IEA Inferred from Electronic Annotation more info
contributes_to chromatin binding	IC Inferred by Curator more info	PubMed
enables helicase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables single-stranded DNA binding	IEA Inferred from Electronic Annotation more info
enables single-stranded DNA helicase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA duplex unwinding	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within DNA replication	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within DNA replication initiation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within DNA strand elongation involved in DNA replication	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within double-strand break repair via break-induced replication	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mitotic DNA replication initiation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of DNA-templated DNA replication initiation	IC Inferred by Curator more info	PubMed
acts_upstream_of_or_within regulation of DNA-templated DNA replication initiation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of CMG complex	ISS Inferred from Sequence or Structural Similarity more info
part_of MCM complex	IDA Inferred from Direct Assay more info	PubMed
part_of MCM complex	IEA Inferred from Electronic Annotation more info
located_in chromosome	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: zygotic DNA replication licensing factor mcm3

Names: MCM3 minichromosome maintenance deficient 3; zmcm3; zygotic Mcm3 protein; zygotic minichromosome maintenance protein 3

NP_001080158.1

EC 3.6.4.12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001086689.1 → NP_001080158.1 zygotic DNA replication licensing factor mcm3

See identical proteins and their annotated locations for NP_001080158.1

Status: PROVISIONAL

Source sequence(s)

BC044051

UniProtKB/Swiss-Prot

Q7ZXZ0

UniProtKB/TrEMBL

A0A090AX62, A0A974CZA0

Related

ENSXLAP00005027308.1, ENSXLAT00005028040.1

Conserved Domains (3) summary

smart00350
Location:109 → 654

MCM; minichromosome maintenance proteins

pfam14551
Location:17 → 129

MCM_N; MCM N-terminal domain

cl21455
Location:340 → 479

P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054379.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

161941031..161961069 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)