dpysl3.S dihydropyrimidinase like 3 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: dpysl3.S
Official Full Name: dihydropyrimidinase like 3 S homeolog
Primary source: Xenbase:XB-GENE-944735
Locus tag: XELAEV_18021408mg
See related: EnsemblRapid:ENSXLAG00005013086 AllianceGenome:Xenbase:XB-GENE-944735
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: drp3; nsp1; tuc4; ulip; crmp4; drp-3; lcrmp; tuc-4; CRMP-4; dpysl3; ulip-1; dpysl3-a; dpysl3-b; dpysl3.L
Summary: Predicted to enable hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds. Predicted to act upstream of or within actin crosslink formation. Predicted to be located in cytoplasm and growth cone. Is expressed in ectoderm; musculoskeletal system; nervous system; and vestibuloauditory system. Orthologous to human DPYSL3 (dihydropyrimidinase like 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 3S

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	3S	NC_054376.1 (103190184..103283666, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	3S	NC_030729.1 (101234920..101328634, complement)

Chromosome 3S - NC_054376.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within actin crosslink formation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cell projection	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in growth cone	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: dihydropyrimidinase-related protein 3-A

Names: DRP-3-A; dihydropyrimidinase like 3 L homeolog; dihydropyrimidinase-like 3; neural-specific protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001086642.1 → NP_001080111.1 dihydropyrimidinase-related protein 3-A

See identical proteins and their annotated locations for NP_001080111.1

Status: PROVISIONAL

Source sequence(s)

Y13069

UniProtKB/Swiss-Prot

O13022, Q7ZWQ8

Related

ENSXLAP00005038623.1, ENSXLAT00005039540.1

Conserved Domains (2) summary

PRK09060
Location:17 → 467

PRK09060; dihydroorotase; Validated

cd01314
Location:17 → 466

D-HYD; D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054376.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

103190184..103283666 complement

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GenBank, FASTA, Sequence Viewer (Graphics)