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pold2.L polymerase (DNA directed), delta 2, accessory subunit L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 379793, updated on 3-Jul-2024

Summary

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Official Symbol
pold2.L
Official Full Name
polymerase (DNA directed), delta 2, accessory subunit L homeolog
Primary source
Xenbase:XB-GENE-999393
Locus tag
XELAEV_18018645mg
See related
EnsemblRapid:ENSXLAG00005002733
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
cdc1; pold2
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Genomic context

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See pold2.L in Genome Data Viewer
Location:
chromosome: 3L
Exon count:
12
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (134590784..134606710)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3L NC_030728.1 (119252647..119268560)

Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene myosin light chain, regulatory A Neighboring gene spermatogenesis associated 18a L homeolog Neighboring gene AE binding protein 1 L homeolog Neighboring gene drebrin like L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterisation of XlCdc1, a Xenopus homologue of the small (PolD2) subunit of DNA polymerase delta; identification of ten conserved regions I-X based on protein sequence comparisons across ten eukaryotic species. Reynolds N, et al. Gene, 1999 Apr 1. PMID 10196469
  2. Protein interactomes of protein phosphatase 2A B55 regulatory subunits reveal B55-mediated regulation of replication protein A under replication stress. Wang F, et al. Sci Rep, 2018 Feb 8. PMID 29422626, Free PMC Article
  3. Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation. Nishiyama A, et al. Nat Commun, 2020 Mar 6. PMID 32144273, Free PMC Article
  4. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC53975

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within DNA repair IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within DNA replication IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of delta DNA polymerase complex IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DNA polymerase delta subunit 2
Names
DNA-directed DNA polymerase delta 2
polymerase (DNA directed), delta 2, regulatory subunit 50kDa
xlCdc1
NP_001080101.1
XP_018106174.1
XP_018106175.1
XP_041440870.1
XP_041440871.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001086632.1 → NP_001080101.1  DNA polymerase delta subunit 2

    See identical proteins and their annotated locations for NP_001080101.1

    Status: PROVISIONAL

    Source sequence(s)
    BC047262
    UniProtKB/Swiss-Prot
    O93610, Q5D0A2
    Conserved Domains (1) summary
    cd07387
    Location:222 → 452
    MPP_PolD2_C; PolD2 (DNA polymerase delta, subunit 2), C-terminal domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    134590784..134606710
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018250685.2 → XP_018106174.1  DNA polymerase delta subunit 2 isoform X1

    UniProtKB/TrEMBL
    A0A1L8H1Q8, A0A974DF91
    Related
    ENSXLAP00005008109.1, ENSXLAT00005008232.1
    Conserved Domains (2) summary
    cd07387
    Location:222 → 452
    MPP_PolD2_C; PolD2 (DNA polymerase delta, subunit 2), C-terminal domain
    pfam18018
    Location:49 → 176
    DNA_pol_D_N; DNA polymerase delta subunit OB-fold domain

  2. XM_018250686.2 → XP_018106175.1  DNA polymerase delta subunit 2 isoform X2

    UniProtKB/TrEMBL
    A0A8J0ULP3
    Conserved Domains (2) summary
    cd07387
    Location:140 → 370
    MPP_PolD2_C; PolD2 (DNA polymerase delta, subunit 2), C-terminal domain
    pfam18018
    Location:49 → 85
    DNA_pol_D_N; DNA polymerase delta subunit OB-fold domain

  3. XM_041584937.1 → XP_041440871.1  DNA polymerase delta subunit 2 isoform X2

    UniProtKB/TrEMBL
    A0A8J0ULP3
    Conserved Domains (2) summary
    cd07387
    Location:140 → 370
    MPP_PolD2_C; PolD2 (DNA polymerase delta, subunit 2), C-terminal domain
    pfam18018
    Location:49 → 85
    DNA_pol_D_N; DNA polymerase delta subunit OB-fold domain

  4. XM_041584936.1 → XP_041440870.1  DNA polymerase delta subunit 2 isoform X1

    UniProtKB/TrEMBL
    A0A1L8H1Q8, A0A974DF91
    Conserved Domains (2) summary
    cd07387
    Location:222 → 452
    MPP_PolD2_C; PolD2 (DNA polymerase delta, subunit 2), C-terminal domain
    pfam18018
    Location:49 → 176
    DNA_pol_D_N; DNA polymerase delta subunit OB-fold domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O93610.1 GenPept UniProtKB/Swiss-Prot:O93610

Gene LinkOut

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