lrrn1.L leucine rich repeat neuronal 1 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: lrrn1.L
Official Full Name: leucine rich repeat neuronal 1 L homeolog
Primary source: Xenbase:XB-GENE-866210
Locus tag: XELAEV_18023906mg
See related: EnsemblRapid:ENSXLAG00005034605 AllianceGenome:Xenbase:XB-GENE-866210
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: lrrn1; nlrr-1; nlrr-6; figler3; lrrn1-a; lrrn1-b; xnlrr-1; XlNLRR-6
Summary: Predicted to be located in synaptic membrane. Is expressed in cardiovascular system; nervous system; pharyngeal arch; and primary germ layer. Orthologous to human LRRN1 (leucine rich repeat neuronal 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 4L

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	4L	NC_054377.1 (129133401..129145894)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	4L	NC_030730.1 (123898408..123910983)

Chromosome 4L - NC_054377.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in synaptic membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: leucine rich repeat neuronal 1 L homeolog

Names: neuronal leucine-rich repeat protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001086525.1 → NP_001079994.1 leucine rich repeat neuronal 1 L homeolog precursor

See identical proteins and their annotated locations for NP_001079994.1

Status: PROVISIONAL

Source sequence(s)

BC059292

UniProtKB/TrEMBL

A0A974D6X6, O73675, Q6PCK4

Related

ENSXLAP00005103440.1, ENSXLAT00005105445.1

Conserved Domains (10) summary

smart00408
Location:441 → 508

IGc2; Immunoglobulin C-2 Type

smart00013
Location:33 → 76

LRRNT; Leucine rich repeat N-terminal domain

smart00082
Location:372 → 418

LRRCT; Leucine rich repeat C-terminal domain

cd00116
Location:92 → 320

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

pfam07679
Location:431 → 518

I-set; Immunoglobulin I-set domain

sd00031
Location:75 → 97

LRR_1; leucine-rich repeat [structural motif]

sd00033
Location:98 → 121

LRR_RI; leucine-rich repeat [structural motif]

pfam00041
Location:538 → 602

fn3; Fibronectin type III domain

pfam12799
Location:97 → 137

LRR_4; Leucine Rich repeats (2 copies)

pfam13855
Location:97 → 156

LRR_8; Leucine rich repeat