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tm7sf2.L transmembrane 7 superfamily member 2 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 379527, updated on 4-Nov-2024

Summary

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Official Symbol
tm7sf2.L
Official Full Name
transmembrane 7 superfamily member 2 L homeolog
Primary source
Xenbase:XB-GENE-1005376
Locus tag
XELAEV_18022118mg
See related
EnsemblRapid:ENSXLAG00005018272 AllianceGenome:Xenbase:XB-GENE-1005376
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
tm7sf2
Summary
Predicted to enable delta14-sterol reductase activity. Predicted to act upstream of or within cholesterol biosynthetic process. Predicted to be located in endoplasmic reticulum membrane and nuclear inner membrane. Orthologous to human TM7SF2 (transmembrane 7 superfamily member 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See tm7sf2.L in Genome Data Viewer
Location:
chromosome: 4L
Exon count:
13
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (23322753..23335718, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (21779123..21786859, complement)

Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene SAC3 domain containing 1 L homeolog Neighboring gene zinc finger HIT-type containing 2 L homeolog Neighboring gene uncharacterized LOC121402966 Neighboring gene soluble toll-like receptor 5 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC68849

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables delta14-sterol reductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cholesterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within sterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in nuclear inner membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
delta(14)-sterol reductase TM7SF2; transmembrane 7 superfamily member 2 L homeolog
XP_041445907.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    23322753..23335718 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041589973.1 → XP_041445907.1  delta(14)-sterol reductase TM7SF2

    UniProtKB/TrEMBL
    A0A1L8GJH4, A0A974D3S4, Q7T0Z1
    Related
    ENSXLAP00005053955.1, ENSXLAT00005055129.1
    Conserved Domains (1) summary
    cl21511
    Location:9 → 420
    PEMT; Phospholipid methyltransferase

RNA

  1. XR_005966906.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001086368.1: Suppressed sequence

    Description
    NM_001086368.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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