rab5d.S RAB5D, member RAS oncogene family S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: rab5d.S
Official Full Name: RAB5D, member RAS oncogene family S homeolog
Primary source: Xenbase:XB-GENE-865873
Locus tag: XELAEV_18047314mg
See related: EnsemblRapid:ENSXLAG00005025425 AllianceGenome:Xenbase:XB-GENE-865873
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: mras; m-ras; rab5d; rras3; r-ras3
Summary: Predicted to enable GTP binding activity and GTPase activity. Predicted to act upstream of or within vesicle-mediated transport. Predicted to be located in early endosome and phagocytic vesicle membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 9_10S

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	9_10S	NC_054388.1 (75831025..75847740, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	9_10S	NC_030741.1 (69190831..69208032, complement)

Chromosome 9_10S - NC_054388.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Mras acts at a late step of neurogenesis and is required for neuronal differentiation.
Title: MRAS GTPase is a novel stemness marker that impacts mouse embryonic stem cell plasticity and Xenopus embryonic cell fate.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in early endosome	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in phagocytic vesicle membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: RAB5D, member RAS oncogene family S homeolog

Names: muscle RAS oncogene homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001086348.2 → NP_001079817.1 RAB5D, member RAS oncogene family S homeolog

See identical proteins and their annotated locations for NP_001079817.1

Status: PROVISIONAL

Source sequence(s)

BC054969

UniProtKB/TrEMBL

Q7SY85

Related

ENSXLAP00005075581.1, ENSXLAT00005077161.1

Conserved Domains (2) summary

cd01860
Location:19 → 181

Rab5_related; Rab-related GTPase family includes Rab5 and Rab22; regulates early endosome fusion

pfam00071
Location:21 → 182

Ras; Ras family

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

75831025..75847740 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_018237186.2 → XP_018092675.1 RAB5D, member RAS oncogene family S homeolog isoform X1

UniProtKB/TrEMBL

A0A1L8EPQ6, A0A974BVN0
XM_018237185.2 → XP_018092674.1 RAB5D, member RAS oncogene family S homeolog isoform X1

UniProtKB/TrEMBL

A0A1L8EPQ6, A0A974BVN0